Literature DB >> 15785283

Comparative efficacy of ropivacaine and bupivacaine infiltrative analgesia in otoplasty.

Despoina Kakagia1, Spartakos Fotiadis, Gregory Tripsiannis.   

Abstract

A prospective double-blind study was conducted to compare the anesthetic efficacy of ropivacaine and bupivacaine in a bilaterally symmetrical otoplasty model. Because ropivacaine has a significantly lower toxic potential than bupivacaine, it may be established as the anesthetic agent of choice for low-dose infiltration anesthesia in routine aesthetic facial operations. Each of the 24 adult patients undergoing bilateral otoplasty received infiltration with ropivacaine in 1 auricle and an equal volume of bupivacaine in the other. Patients were requested to assess their pain separately in each side at the times of infiltration, during cartilage scoring, and 2, 6, and 10 hours postoperatively on a visual analog scale. Intraoperative success rates were similar, and overall analgesia achieved at 2 hours, 6 hours, and 10 hours postoperatively was not found to be statistically different between ropivacaine and bupivacaine. The authors conclude that ropivacaine can be used as an effective alternative to bupivacaine in otoplasty.

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Year:  2005        PMID: 15785283     DOI: 10.1097/01.sap.0000151460.74629.b2

Source DB:  PubMed          Journal:  Ann Plast Surg        ISSN: 0148-7043            Impact factor:   1.539


  3 in total

Review 1.  Ropivacaine: a review of its use in regional anaesthesia and acute pain management.

Authors:  Dene Simpson; Monique P Curran; Vicki Oldfield; Gillian M Keating
Journal:  Drugs       Date:  2005       Impact factor: 9.546

2.  The local pharmacokinetics of ³H-ropivacaine and ¹⁴C-lidocaine after maxillary infiltration anesthesia in rats.

Authors:  Hiromi Kimi; Mikiko Yamashiro; Shuichi Hashimoto
Journal:  Anesth Prog       Date:  2012

3.  Epinephrine Affects Pharmacokinetics of Ropivacaine Infiltrated Into Palate.

Authors:  Mikiko Yamashiro; Shuichi Hashimoto; Asako Yasuda; Katsuhisa Sunada
Journal:  Anesth Prog       Date:  2016
  3 in total

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