Literature DB >> 15782538

[Superficial mycoses: comparative study between type 2 diabetic patients and a non-diabetic control group].

Leila García-Humbría1, Nicole Richard-Yegres, Maigualida Pérez-Blanco, Francisco Yegres, Mireya Mendoza, Arnaldo Acosta, Rosaura Hernández, Eluz Zárraga.   

Abstract

Superficial mycoses are considered to affect more frequently patients with type 2 diabetes mellitus (DM-2), specially onychomycosis and Tinea pedis. The purpose of this study was to compare the dermatophytoses, candidiasis and Pitiriasis versicolor frequency between 40 patients with DM-2 and 40 healthy persons of either sex, 40 years old or more. Clinical, metabolic, mycologic and inmunologic studies against Candida albicans, were carried out. Both diabetics 75% (30/40) and controls 65% (26/40) presented a high frequency of superficial mycoses (no significant difference p = 0.329). Pitiriasis versicolor was not detected in diabetic patients. They presented Tinea unguium, concomitant with Tinea pedis, with a higher frequency. The predominant dermatophyte was Trichophyton rubrum 18/23 (78%) in diabetics and 8/16 (50%) in non diabetics. Candida was isolated as commensal from oral mucous: 23/40 (58%) in diabetics and 21/40 (52%) in non diabetics (serotipo A was the more frequent), and from onychomycosis: 11/40 (28%) in diabetics and 12/40 (30%) in non diabetics. The immunological response was the same in both groups: celular 100%, humoral 20%. No statistical correlation among superficial mycoses, blood glucose level, glycosylated hemoglobin values or the time suffering the disease was observed. The high susceptibility to dermatophytes and Candida sp. infection showed to be associated with age and no with the diabetic type 2 condition in those patients.

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Year:  2005        PMID: 15782538

Source DB:  PubMed          Journal:  Invest Clin        ISSN: 0535-5133            Impact factor:   0.683


  3 in total

1.  Epidemiological, clinical and mycological study of dermatomycosis in diabetic patients.

Authors:  Sarra Cheikhrouhou; Amal Attoini; Dorsaf Aloui; Meriam Bouchekoua; Sonia Trabelsi; Samira Khaled
Journal:  Tunis Med       Date:  2021 Aout

2.  Antifungal activity of alexidine dihydrochloride in a novel diabetic mouse model of dermatophytosis.

Authors:  Sunna Nabeela; Abhijit Date; Ashraf S Ibrahim; Priya Uppuluri
Journal:  Front Cell Infect Microbiol       Date:  2022-09-02       Impact factor: 6.073

3.  [What agents incriminated in athlete's foot? Survey of consulting diabetic patients in CHU Mohammed VI Marrakech].

Authors:  Hakima Chegour; Nawal El Ansari; Ghizlane El Mghari; Abdelali Tali; Laila Zoughaghi; Majda Sebbani; Mohamed Amine
Journal:  Pan Afr Med J       Date:  2014-03-26
  3 in total

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