Anne Pitkäranta1, Kaija-Leena Kolho, Hilpi Rautelin. 1. Department of Otorhinolaryngology, Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland. anne.pitkaranta@hus.fi
Abstract
OBJECTIVE: To examine the presence of Helicobacter pylori infection in children with recurrent upper respiratory infections, including acute otitis media. DESIGN: A prospective clinical trial. SETTING: Tertiary referral center. PATIENTS: A total of 20 children who were prone to upper respiratory infections and acute otitis and who were admitted for elective adenoidectomy and/or tympanostomy were included in the study. MAIN OUTCOME MEASURES: Samples of adenoid tissue and middle ear fluid were cultured for H pylori. Serologic analysis and fecal antigen detection testing were also carried out to determine the presence of H pylori. RESULTS: The results of serologic and antigen detection tests were positive for H pylori in 4 children (20%), but cultures of adenoid tissue and middle ear fluid samples were negative for H pylori in all children. CONCLUSION: An association between H pylori infection and recurrent upper respiratory infections and otitis media could not be established.
OBJECTIVE: To examine the presence of Helicobacter pyloriinfection in children with recurrent upper respiratory infections, including acute otitis media. DESIGN: A prospective clinical trial. SETTING: Tertiary referral center. PATIENTS: A total of 20 children who were prone to upper respiratory infections and acute otitis and who were admitted for elective adenoidectomy and/or tympanostomy were included in the study. MAIN OUTCOME MEASURES: Samples of adenoid tissue and middle ear fluid were cultured for H pylori. Serologic analysis and fecal antigen detection testing were also carried out to determine the presence of H pylori. RESULTS: The results of serologic and antigen detection tests were positive for H pylori in 4 children (20%), but cultures of adenoid tissue and middle ear fluid samples were negative for H pylori in all children. CONCLUSION: An association between H pyloriinfection and recurrent upper respiratory infections and otitis media could not be established.
Authors: S Kariya; M Okano; K Fukushima; S Nomiya; Y Kataoka; R Nomiya; H Akagi; K Nishizaki Journal: Clin Exp Immunol Date: 2008-08-22 Impact factor: 4.330
Authors: Laith Khasawneh; Adi H Khassawneh; Khalid A Kheirallah; Giampiero Neri; Giulio Filograna Pignatelli; Hasan Ibrahim Al-Balas; Stefano Martinotti; Abdel-Hameed Al-Mistarehi Journal: Ann Med Surg (Lond) Date: 2021-01-24