Literature DB >> 15781765

The prevalence of "incidental" acoustic neuroma.

Doris Lin1, Joseph L Hegarty, Nancy J Fischbein, Robert K Jackler.   

Abstract

OBJECTIVE: To estimate the prevalence of "incidental" acoustic neuromas (ANs) in the population at large.
DESIGN: An intracranial magnetic resonance imaging (MRI) database of 46 414 patients presenting to the University of California, San Francisco (UCSF), without known audiovestibular complaints was searched retrospectively from July 1995 to February 2003. Seventy percent of these MRIs included gadolinium, and none was specifically targeted through the internal auditory canal. A medical chart review of 688 patients with acoustic neuromas presenting to UCSF between 1980 and 1999 was searched for sex distribution.
SETTING: Tertiary care university medical center.
RESULTS: Eight patients with incidental AN were discovered. This figure suggests that undiagnosed ANs may be present in at least 0.02% of the population. Three patients were found to have audiovestibular symptoms on inquiry after diagnosis. Audiometry revealed asymmetry at 4 kHz in only 3 of 7 patients, with an otherwise symmetric audiogram in the remaining patients. Tumor size in this population ranged from 3 to 28 mm. Incidental ANs were more common in men, but ANs were more common in women overall.
CONCLUSIONS: The prevalence of incidental AN appears to be roughly 2 in 10,000 people. This figure indicates that AN may be less prevalent than suggested in previously reported temporal bone studies and more prevalent than suggested by epidemiologic studies.

Entities:  

Mesh:

Year:  2005        PMID: 15781765     DOI: 10.1001/archotol.131.3.241

Source DB:  PubMed          Journal:  Arch Otolaryngol Head Neck Surg        ISSN: 0886-4470


  34 in total

1.  Rule 3,000: a more reliable precursor to perceive vestibular schwannoma on MRI in screened asymmetric sensorineural hearing loss.

Authors:  Issam Saliba; Mathieu Bergeron; Geneviève Martineau; Miguel Chagnon
Journal:  Eur Arch Otorhinolaryngol       Date:  2010-09-11       Impact factor: 2.503

2.  Incidence of vestibular schwannomas in the United States.

Authors:  Varun R Kshettry; Jason K Hsieh; Quinn T Ostrom; Carol Kruchko; Jill S Barnholtz-Sloan
Journal:  J Neurooncol       Date:  2015-05-30       Impact factor: 4.130

3.  Cost-effectiveness analysis of a non-contrast screening MRI protocol for vestibular schwannoma in patients with asymmetric sensorineural hearing loss.

Authors:  Matthew G Crowson; Daniel J Rocke; Jenny K Hoang; Jane L Weissman; David M Kaylie
Journal:  Neuroradiology       Date:  2017-06-16       Impact factor: 2.804

4.  Auditory Pathway Features Determined by DTI in Subjects with Unilateral Acoustic Neuroma.

Authors:  S Kurtcan; A Alkan; R Kilicarslan; A A Bakan; H Toprak; A Aralasmak; F Aksoy; A Kocer
Journal:  Clin Neuroradiol       Date:  2015-03-27       Impact factor: 3.649

Review 5.  [Imaging-based diagnosis of vestibular schwannoma].

Authors:  C Strasilla; V Sychra
Journal:  HNO       Date:  2017-05       Impact factor: 1.284

6.  Long-term outcomes of vestibular schwannomas treated with fractionated stereotactic radiotherapy: an institutional experience.

Authors:  Sumit Kapoor; Sachin Batra; Kathryn Carson; John Shuck; Siddharth Kharkar; Rahul Gandhi; Juan Jackson; Jan Wemmer; Stephanie Terezakis; Ori Shokek; Lawrence Kleinberg; Daniele Rigamonti
Journal:  Int J Radiat Oncol Biol Phys       Date:  2010-09-29       Impact factor: 7.038

7.  [Imaging of acoustic neuroma (vestibular schwannoma). Breakthrough or dilemma?].

Authors:  E Hofmann; L Choné
Journal:  HNO       Date:  2011-01       Impact factor: 1.284

8.  Increased Operative Time for Benign Cranial Nerve Tumor Resection Correlates with Increased Morbidity Postoperatively.

Authors:  Meghan Murphy; Hannah Gilder; Brandon A McCutcheon; Panagiotis Kerezoudis; Lorenzo Rinaldo; Daniel Shepherd; Patrick Maloney; Kendall Snyder; Matthew L Carlson; Bob S Carter; Mohamad Bydon; Jamie J Van Gompel; Michael J Link
Journal:  J Neurol Surg B Skull Base       Date:  2016-02-13

9.  An in vitro model system to study gene therapy in the human inner ear.

Authors:  B W Kesser; G T Hashisaki; K Fletcher; H Eppard; J R Holt
Journal:  Gene Ther       Date:  2007-06-14       Impact factor: 5.250

10.  Prevalence of Sporadic Vestibular Schwannoma: Reconciling Temporal Bone, Radiologic, and Population-based Studies.

Authors:  John P Marinelli; Brandon R Grossardt; Christine M Lohse; Matthew L Carlson
Journal:  Otol Neurotol       Date:  2019-03       Impact factor: 2.311

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