Literature DB >> 15781363

Results from a degradable TMC joint Spacer (Artelon) compared with tendon arthroplasty.

Anders Nilsson1, Elisabeth Liljensten, Christina Bergström, Christer Sollerman.   

Abstract

PURPOSE: A new spacer for the trapeziometacarpal joint (TMC) based on a biological and tissue-preserving concept for the treatment of TMC osteoarthritis (OA) has been evaluated. The purpose was to combine a spacing effect with stabilization of the TMC joint.
METHODS: Artelon (Artimplant AB, Sweden) TMC Spacer is synthesized of a degradable polyurethaneurea (Artelon), which has been shown to be biocompatible over time and currently is used in ligament augmentation procedures. Fibers of the polymer were woven into a T-shaped device in which the vertical portion separates the bone edges of the TMC joint and the horizontal portion stabilizes the joint. Fifteen patients with disabling pain and isolated TMC OA were included in the study. Ten patients received the spacer device and the remaining 5 (control group) were treated with a trapezium resection arthroplasty with abductor pollicis longus (APL) stabilization. The median ages of the 2 groups were 60 and 59 years, respectively. Pain, strength, stability, and range of motion were measured before and after surgery. Radiographic examination was performed in all patients before and after surgery. At follow-up evaluation 3 years after surgery an unbiased observer evaluated all patients. Biopsy specimens were obtained from 1 patient 6 months after surgery.
RESULTS: All patients were stable clinically without signs of synovitis. In both groups all patients were pain free. The median values for both key pinch and tripod pinch increased compared with before surgery in the spacer group but not in the APL group. The biopsy examinations showed incorporation of the device in the surface of the adjacent bone and the surrounding connective tissue. No signs of foreign-body reaction were seen.
CONCLUSIONS: This study showed significantly better pinch strength after Artelon TMC Spacer implantation into the TMC joint compared with APL arthroplasty.

Entities:  

Mesh:

Substances:

Year:  2005        PMID: 15781363     DOI: 10.1016/j.jhsa.2004.12.001

Source DB:  PubMed          Journal:  J Hand Surg Am        ISSN: 0363-5023            Impact factor:   2.230


  23 in total

1.  Complications with the use of Artelon in thumb CMC joint arthritis.

Authors:  Sylvan Clarke; William Hagberg; Robert A Kaufmann; Aaron Grand; Ronit Wollstein
Journal:  Hand (N Y)       Date:  2011-04-09

2.  Trapeziometacarpal joint arthritis.

Authors:  Tejas J Patel; Pedro K Beredjiklian; Jonas L Matzon
Journal:  Curr Rev Musculoskelet Med       Date:  2013-03

3.  Increased Complications in Trapeziectomy With Ligament Reconstruction and Tendon Interposition Compared With Trapeziectomy Alone.

Authors:  Aparajit Naram; Keith Lyons; Douglas M Rothkopf; Edward R Calkins; Thomas Breen; Marci Jones; John V Shufflebarger
Journal:  Hand (N Y)       Date:  2016-01-14

4.  Clinical Evaluation of the Articulinx Intercarpometacarpal Cushion for the First CMC Joint: A Feasibility Study.

Authors:  Fiente J C van der Veen; David N White; Mattie M L Dapper; J Peter W Don Griot; Marco P J F Ritt
Journal:  J Wrist Surg       Date:  2013-08

Review 5.  Surgical treatment of trapeziometacarpal joint arthritis: a historical perspective.

Authors:  Vincent R Hentz
Journal:  Clin Orthop Relat Res       Date:  2014-04       Impact factor: 4.176

6.  A minimal wrist arthroplasty for early wrist osteoarthritis.

Authors:  Ronit Wollstein; Lois Carlson
Journal:  J Wrist Surg       Date:  2013-05

7.  The Artelon CMC spacer compared with tendon interposition arthroplasty.

Authors:  Anders Nilsson; Monica Wiig; Håkan Alnehill; Magnus Berggren; Sten Björnum; Mats Geijer; Philippe Kopylov; Christer Sollerman
Journal:  Acta Orthop       Date:  2010-04       Impact factor: 3.717

8.  Adhesion and collagen production of human tenocytes seeded on degradable poly(urethane urea).

Authors:  Laura Ruzzini; Umile Giuseppe Longo; Stefano Campi; Nicola Maffulli; Andrea Onetti Muda; Vincenzo Denaro
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2012-10-18       Impact factor: 4.342

9.  Surgical treatment of thumb carpometacarpal joint arthritis: a single institution experience from 1995-2005.

Authors:  Min J Park; Greg Lichtman; Jennifer B Christian; Jennifer Weintraub; James Chang; Vincent R Hentz; Amy L Ladd; Jeffrey Yao
Journal:  Hand (N Y)       Date:  2008-06-05

10.  Characterization of a new degradable polymer scaffold for regeneration of the dermis: In vitro and in vivo human studies.

Authors:  Fredrik Rm Huss; Erika Nyman; Carl-Johan Gustafson; Katrin Gisselfält; Elisabeth Liljensten; Gunnar Kratz
Journal:  Organogenesis       Date:  2008-07       Impact factor: 2.500

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.