R P Shellis1, M Addy, G D Rees. 1. Division of Restorative Dentistry, University of Bristol Dental School, Lower Maudlin Street, Bristol BS1 2LY, UK. r.p.shellis@bris.ac.uk
Abstract
OBJECTIVES: To study properties of sodium tripolyphosphate (STP) relevant to inhibition or removal of dental stain in vitro. METHODS: The effects of STP and other phosphates on adsorption of a dietary chromogen (black tea polyphenol) and salivary protein to hydroxyapatite (HA) powder were studied by analysing loss of protein or tea stain from solutions mixed with HA or HA pre-treated with the test agents. The effects on desorption of protein and stain from HA were studied by analysis of water or solutions of test agents mixed with HA or HA pre-treated with saliva or tea solution. RESULTS: At concentrations and pH representative of those likely to occur in the mouth, STP inhibited adsorption of salivary protein and black tea polyphenol to, and desorbed these substances from, HA surfaces. Adsorption and desorption of protein and stain were not influenced by pH of the STP solutions but adsorption varied with concentration. STP showed equivalent effectiveness with respect to salivary protein adsorption and desorption as a longer-chain condensed phosphate. The inhibitory activity of HA-bound STP on adsorption of salivary protein and stain resisted extensive washing. CONCLUSIONS: STP is likely to be an effective agent for inhibiting and removing dental stain, whether bound directly to mineralised surfaces or indirectly via salivary pellicle.
OBJECTIVES: To study properties of sodium tripolyphosphate (STP) relevant to inhibition or removal of dental stain in vitro. METHODS: The effects of STP and other phosphates on adsorption of a dietary chromogen (black teapolyphenol) and salivary protein to hydroxyapatite (HA) powder were studied by analysing loss of protein or tea stain from solutions mixed with HA or HA pre-treated with the test agents. The effects on desorption of protein and stain from HA were studied by analysis of water or solutions of test agents mixed with HA or HA pre-treated with saliva or tea solution. RESULTS: At concentrations and pH representative of those likely to occur in the mouth, STP inhibited adsorption of salivary protein and black teapolyphenol to, and desorbed these substances from, HA surfaces. Adsorption and desorption of protein and stain were not influenced by pH of the STP solutions but adsorption varied with concentration. STP showed equivalent effectiveness with respect to salivary protein adsorption and desorption as a longer-chain condensed phosphate. The inhibitory activity of HA-bound STP on adsorption of salivary protein and stain resisted extensive washing. CONCLUSIONS:STP is likely to be an effective agent for inhibiting and removing dental stain, whether bound directly to mineralised surfaces or indirectly via salivary pellicle.
Authors: Xiaobei Wang; Zhenshan Jia; Yosif Almoshari; Subodh M Lele; Richard A Reinhardt; Dong Wang Journal: Pharm Res Date: 2018-06-25 Impact factor: 4.200
Authors: Barry W Hyland; Ailbhe McDonald; Nicholas Lewis; Christopher Tredwin; Aviva Petrie; Sean Hall; Chris Todd; Bridgeen McCaughan; John F Callan Journal: Clin Oral Investig Date: 2014-11-09 Impact factor: 3.573
Authors: F Ali; P L Sangwan; S Koul; A Pandey; S Bani; S T Abdullah; P R Sharma; S Kitchlu; I A Khan Journal: Eur J Clin Microbiol Infect Dis Date: 2011-05-19 Impact factor: 3.267
Authors: Fu Chen; Zhenshan Jia; Kelly C Rice; Richard A Reinhardt; Kenneth W Bayles; Dong Wang Journal: Pharm Res Date: 2013-06-14 Impact factor: 4.200