Literature DB >> 15781025

Effect of noradrenaline and isoproterenol on lipopolysaccharide-induced tumor necrosis factor-alpha production in whole blood from patients with chronic heart failure and the role of beta-adrenergic receptors.

Stephan von Haehling1, Sabine Genth-Zotz, Aidan P Bolger, Paul R Kalra, Michael Kemp, Ian M Adcock, Philip A Poole-Wilson, Rainer Dietz, Stefan D Anker.   

Abstract

Increased levels of tumor necrosis factor-alpha (TNF-alpha) correlate with poor prognoses in chronic heart failure (CHF). This study demonstrated that noradrenaline and isoproterenol inhibit TNF-alpha production in patients with CHF in ex vivo whole blood in a dose-dependent fashion. The beta-blocker bisoprolol abolishes this effect.

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Year:  2005        PMID： 15781025     DOI： 10.1016/j.amjcard.2004.12.022

Source DB:  PubMed          Journal:  Am J Cardiol        ISSN： 0002-9149            Impact factor:   2.778


  7 in total

Review 1.  Targeting the Microbiome in Heart Failure.

Authors:  Allyson Zabell; W H Wilson Tang
Journal:  Curr Treat Options Cardiovasc Med       Date:  2017-04

2.  Beta-blocker therapy and hemophagocytic lymphohistiocytosis: a case report.

Authors:  C Müller; L B Mänhardt; C Willaschek; E M Schneider; E A Stuth; R Buchhorn
Journal:  Cardiol Res Pract       Date:  2010-06-20       Impact factor: 1.866

3.  Influence of acute epinephrine infusion on endotoxin-induced parameters of heart rate variability: a randomized controlled trial.

Authors:  Badar U Jan; Susette M Coyle; Leo O Oikawa; Shou-En Lu; Steve E Calvano; Paul M Lehrer; Stephen F Lowry
Journal:  Ann Surg       Date:  2009-05       Impact factor: 12.969

4.  Impaired norepinephrine regulation of monocyte inflammatory cytokine balance in heart failure.

Authors:  Tien Mh Ng; Myron L Toews
Journal:  World J Cardiol       Date:  2016-10-26

5.  Effects of epinephrine on heart rate variability and cytokines in a rat sepsis model.

Authors:  Yun-Te Chang; Wei-Chun Huang; Chin-Chang Cheng; Meng-Wei Ke; Jung-Shun Tsai; Yao-Min Hung; Neng-Chyan Huang; Mu-Shun Huang; Shue-Ren Wann
Journal:  Bosn J Basic Med Sci       Date:  2020-02-05       Impact factor: 3.363

6.  Leukocyte redistribution: effects of beta blockers in patients with chronic heart failure.

Authors:  Stephan von Haehling; Joerg C Schefold; Ewa Jankowska; Wolfram Doehner; Jochen Springer; Kristin Strohschein; Sabine Genth-Zotz; Hans-Dieter Volk; Philip Poole-Wilson; Stefan D Anker
Journal:  PLoS One       Date:  2009-07-29       Impact factor: 3.240

7.  Bisoprolol in the treatment of chronic heart failure: from pathophysiology to clinical pharmacology and trial results.

Authors:  Marco Metra; Savina Nodari; Tania Bordonali; Patrizia Milani; Carlo Lombardi; Silvia Bugatti; Benedetta Fontanella; Giulia Verzura; Rossella Danesi; Livio Dei Cas
Journal:  Ther Clin Risk Manag       Date:  2007-08       Impact factor: 2.423
  7 in total

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