Literature DB >> 15780930

Transcriptional activation: mediator can act after preinitiation complex formation.

Kevin Struhl1.   

Abstract

The Mediator complex connects transcriptional activators bound at enhancers with RNA polymerase (Pol) II. demonstrate that Mediator also has an important role in transcriptional activation after recruitment of the Pol II machinery to promoters.

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Year:  2005        PMID: 15780930     DOI: 10.1016/j.molcel.2005.03.002

Source DB:  PubMed          Journal:  Mol Cell        ISSN: 1097-2765            Impact factor:   17.970


  11 in total

1.  Mediator complex regulates alternative mRNA processing via the MED23 subunit.

Authors:  Yan Huang; Wencheng Li; Xiao Yao; Qi-Jiang Lin; Jing-Wen Yin; Yan Liang; Monika Heiner; Bin Tian; Jingyi Hui; Gang Wang
Journal:  Mol Cell       Date:  2012-01-19       Impact factor: 17.970

2.  Dynamic and transient remodeling of the macrophage IL-10 promoter during transcription.

Authors:  Xia Zhang; Justin P Edwards; David M Mosser
Journal:  J Immunol       Date:  2006-07-15       Impact factor: 5.422

3.  Lineage-specific activators affect beta-globin locus chromatin in multipotent hematopoietic progenitors.

Authors:  Stefania Bottardi; Julie Ross; Natacha Pierre-Charles; Volker Blank; Eric Milot
Journal:  EMBO J       Date:  2006-07-13       Impact factor: 11.598

4.  Expression noise and acetylation profiles distinguish HDAC functions.

Authors:  Leehee Weinberger; Yoav Voichek; Itay Tirosh; Gil Hornung; Ido Amit; Naama Barkai
Journal:  Mol Cell       Date:  2012-06-07       Impact factor: 17.970

5.  Transcriptional enhancers in animal development and evolution.

Authors:  Mike Levine
Journal:  Curr Biol       Date:  2010-09-14       Impact factor: 10.834

Review 6.  Mediator kinase module and human tumorigenesis.

Authors:  Alison D Clark; Marieke Oldenbroek; Thomas G Boyer
Journal:  Crit Rev Biochem Mol Biol       Date:  2015-07-16       Impact factor: 8.250

Review 7.  Distinct regulatory mechanisms of eukaryotic transcriptional activation by SAGA and TFIID.

Authors:  Sukesh R Bhaumik
Journal:  Biochim Biophys Acta       Date:  2010-08-26

8.  Activation of a poised RNAPII-dependent promoter requires both SAGA and mediator.

Authors:  Sarah K Lee; Aaron G L Fletcher; Lei Zhang; Xu Chen; Julie A Fischbeck; Laurie A Stargell
Journal:  Genetics       Date:  2010-01-04       Impact factor: 4.562

9.  Non-DNA-binding cofactors enhance DNA-binding specificity of a transcriptional regulatory complex.

Authors:  Trevor Siggers; Michael H Duyzend; Jessica Reddy; Sidra Khan; Martha L Bulyk
Journal:  Mol Syst Biol       Date:  2011-12-06       Impact factor: 11.429

10.  The mRNA cap-binding complex stimulates the formation of pre-initiation complex at the promoter via its interaction with Mot1p in vivo.

Authors:  Shweta Lahudkar; Abhijit Shukla; Pratibha Bajwa; Geetha Durairaj; Nadia Stanojevic; Sukesh R Bhaumik
Journal:  Nucleic Acids Res       Date:  2010-11-12       Impact factor: 16.971

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