Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Linking Rap to cell adhesion.

Literature DB >> 15780587

Linking Rap to cell adhesion.

Abstract

The small GTPase Rap1 is involved in several aspects of cell adhesion, including integrin-mediated cell adhesion and cadherin-mediated cell junction formation. Recently, several effector proteins for Rap1 have been identified providing a clear link between Rap1 and actin dynamics. Furthermore, evidence is accumulating that Rap1 functions in the spatial and temporal control of cell polarity.

Entities: Gene

Mesh：

Substances：

Year: 2005 PMID： 15780587 DOI： 10.1016/j.ceb.2005.02.009

Source DB: PubMed Journal: Curr Opin Cell Biol ISSN： 0955-0674 Impact factor: 8.382

Keyword Cloud
Cited

193 in total

1. Mesoderm migration in Drosophila is a multi-step process requiring FGF signaling and integrin activity.

Authors: Amy McMahon; Gregory T Reeves; Willy Supatto; Angelike Stathopoulos
Journal: Development Date: 2010-07 Impact factor: 6.868

Review 2. Regulation of the inflammatory response of vascular endothelial cells by EPAC1.

Authors: Euan Parnell; Brian O Smith; Timothy M Palmer; Anna Terrin; Manuela Zaccolo; Stephen J Yarwood
Journal: Br J Pharmacol Date: 2012-05 Impact factor: 8.739

3. Regulation of actin cytoskeleton by Rap1 binding to RacGEF1.

Authors: Hyemin Mun; Taeck J Jeon
Journal: Mol Cells Date: 2012-05-25 Impact factor: 5.034

4. A talin mutant that impairs talin-integrin binding in platelets decelerates αIIbβ3 activation without pathological bleeding.

Authors: Lucia Stefanini; Feng Ye; Adam K Snider; Kasra Sarabakhsh; Raymond Piatt; David S Paul; Wolfgang Bergmeier; Brian G Petrich
Journal: Blood Date: 2014-02-28 Impact factor: 22.113

Linking Rap to cell adhesion.

1. Mesoderm migration in Drosophila is a multi-step process requiring FGF signaling and integrin activity.

Review 2. Regulation of the inflammatory response of vascular endothelial cells by EPAC1.

3. Regulation of actin cytoskeleton by Rap1 binding to RacGEF1.

4. A talin mutant that impairs talin-integrin binding in platelets decelerates αIIbβ3 activation without pathological bleeding.

5. Defective angiogenesis, endothelial migration, proliferation, and MAPK signaling in Rap1b-deficient mice.

6. RAP-1 and the RAL-1/exocyst pathway coordinate hypodermal cell organization in Caenorhabditis elegans.

Review 7. Multiple roles of Rap1 in hematopoietic cells: complementary versus antagonistic functions.

Review 8. The Mystery of Rap1 Suppression of Oncogenic Ras.

9. The structure of an interdomain complex that regulates talin activity.

10. NSP-CAS Protein Complexes: Emerging Signaling Modules in Cancer.