| Literature DB >> 1578052 |
T Vassal1, O Piot, Z Mallat, D Lesage, B Guidet, G Offenstadt.
Abstract
The case of a 68-year-old man suffering from pneumococcal meningoencephalitis is reported. Antibacterial susceptibility tests revealed a multiply resistant pneumococcal strain. High doses of cefotaxime were necessary to sterilize the cerebrospinal fluid despite the achievement of a satisfactory level of antibiotic in the cerebrospinal fluid with moderate dosage. In France, as well as in many countries, high doses of third-generation cephalosporins such as cefotaxime or ceftriaxone should be administered for the initial therapy of suspected pneumococcal meningitis.Entities:
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Year: 1992 PMID： 1578052 DOI： 10.1007/bf01706430
Source DB: PubMed Journal: Intensive Care Med ISSN： 0342-4642 Impact factor: 17.440