Literature DB >> 15777261

The brown adipose cell: a unique model for understanding the molecular mechanism of insulin resistance.

Angela M Valverde1, Manuel Benito.   

Abstract

Type 2 diabetes mellitus (NIDDM) is a complex metabolic disease that occurs when insulin secretion can no longer compensate insulin resistance in peripheral tissues. At the molecular level, insulin resistance correlates with impaired insulin signaling. This review provides new insights into the molecular mechanisms of insulin action and resistance in brown adipose tissue (BAT) and pinpoints the role of BAT in the control of glucose homeostasis.

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Year:  2005        PMID： 15777261     DOI： 10.2174/1389557053175380

Source DB:  PubMed          Journal:  Mini Rev Med Chem        ISSN： 1389-5575            Impact factor:   3.862


  6 in total

1.  Effects of burn injury, cold stress and cutaneous wound injury on the morphology and energy metabolism of murine brown adipose tissue (BAT) in vivo.

Authors:  Edward A Carter; Ali A Bonab; Victoria Hamrahi; Justin Pitman; Daniel Winter; Lacey J Macintosh; Erika M Cyr; Kasie Paul; John Yerxa; Walter Jung; Ronald G Tompkins; Alan J Fischman
Journal:  Life Sci       Date:  2011-05-04       Impact factor: 5.037

2.  Association of heat production with 18F-FDG accumulation in murine brown adipose tissue after stress.

Authors:  Edward A Carter; Ali A Bonab; Kasie Paul; John Yerxa; Ronald G Tompkins; Alan J Fischman
Journal:  J Nucl Med       Date:  2011-09-13       Impact factor: 10.057

3.  Quantitative assessment of brown adipose tissue metabolic activity and volume using 18F-FDG PET/CT and β3-adrenergic receptor activation.

Authors:  M Reza Mirbolooki; Cristian C Constantinescu; Min-Liang Pan; Jogeshwar Mukherjee
Journal:  EJNMMI Res       Date:  2011-12-01       Impact factor: 3.138

4.  Abnormalities in osteoclastogenesis and decreased tumorigenesis in mice deficient for ovarian cancer G protein-coupled receptor 1.

Authors:  Hui Li; Dongmei Wang; Lisam Shanjukumar Singh; Michael Berk; Haiyan Tan; Zhenwen Zhao; Rosemary Steinmetz; Kashif Kirmani; Gang Wei; Yan Xu
Journal:  PLoS One       Date:  2009-05-28       Impact factor: 3.240

5.  Important genetic checkpoints for insulin resistance in salt-sensitive (S) Dahl rats.

Authors:  Marlene F Shehata
Journal:  Cardiovasc Diabetol       Date:  2008-06-21       Impact factor: 9.951

Review 6.  Classification of Therapeutic and Experimental Drugs for Brown Adipose Tissue Activation: Potential Treatment Strategies for Diabetes and Obesity.

Authors:  Jogeshwar Mukherjee; Aparna Baranwal; Kimberly N Schade
Journal:  Curr Diabetes Rev       Date:  2016
  6 in total

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