| Literature DB >> 1577665 |
P A Lartey1, S L DeNinno, R Faghih, D J Hardy, J J Clement, J J Plattner.
Abstract
Novel analogs of (9R)-9-deoxo-9-(N,N-dimethylamino)erythromycin A bearing N-alkylamino substituents at the C-21 position were synthesized. These compounds retained antibacterial activity. The C-21, N,N-dimethylamino analog showed a modest improvement in activity against some Gram-negative bacteria.Entities:
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Year: 1992 PMID: 1577665 DOI: 10.7164/antibiotics.45.380
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN: 0021-8820 Impact factor: 2.649