| Literature DB >> 1577614 |
B L Malpani1, G V Kadival, A M Samuel.
Abstract
Radioimmunoscintigraphic approach could provide a viable non-invasive alternative for the diagnosis of deeply situated tuberculomas. We have evaluated this in a rabbit model constructed to give a characteristic localized tubercular lesion, with complimentary morphological, histological and antigenic profiles. 131I-anti Myobacterium bovis (BCG) antibody was shown to localize at the lesion, where as 131I-bovine serum albumin and 99mTc-red blood cell scans were negative. The clearance of intradermally-injected tuberculous antigen could be traced into ascending lymph nodes using 131I-anti M. bovis (BCG) antibody.Entities:
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Year: 1992 PMID： 1577614 DOI： 10.1016/0883-2897(92)90184-z
Source DB: PubMed Journal: Int J Rad Appl Instrum B ISSN： 0883-2897