Literature DB >> 1577456

Confirmation of the human cathepsin B gene (CTSB) assignment to chromosome 8.

D Fong1, M M Chan, W T Hsieh, J C Menninger, D C Ward.   

Abstract

Human cathepsin B gene (CTSB) has been mapped to two locations: 8p22 and 13q14. Here we confirm the chromosome 8 assignment by three independent methods: (1) analysis of human-hamster somatic cell hybrid DNA by polymerase chain reaction; (2) comparison of hybridization signals to cathepsin B in interphase nuclei of normal fibroblasts and fibroblasts with a chromosome 8 deletion; and (3) fluorescence in situ hybridization to metaphase spreads using cathepsin B cosmid clones. Our results indicate that human CTSB is located at 8p22-p23.1.

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Year:  1992        PMID： 1577456     DOI： 10.1007/bf00207033

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  16 in total

1.  In situ hybridization banding of human chromosomes with Alu-PCR products: a simultaneous karyotype for gene mapping studies.

Authors:  A Baldini; D C Ward
Journal:  Genomics       Date:  1991-04       Impact factor: 5.736

2.  High-resolution mapping of human chromosome 11 by in situ hybridization with cosmid clones.

Authors:  P Lichter; C J Tang; K Call; G Hermanson; G A Evans; D Housman; D C Ward
Journal:  Science       Date:  1990-01-05       Impact factor: 47.728

Review 3.  Cathepsin B and cystatins: evidence for a role in cancer progression.

Authors:  B F Sloane
Journal:  Semin Cancer Biol       Date:  1990-04       Impact factor: 15.707

4.  Isolation of a cDNA clone for the human lysosomal proteinase cathepsin B.

Authors:  D Fong; D H Calhoun; W T Hsieh; B Lee; R D Wells
Journal:  Proc Natl Acad Sci U S A       Date:  1986-05       Impact factor: 11.205

5.  Improvement of PCR amplified DNA sequencing with the aid of detergents.

Authors:  B Bachmann; W Lüke; G Hunsmann
Journal:  Nucleic Acids Res       Date:  1990-03-11       Impact factor: 16.971

6.  Mapping of the gene for human cysteine proteinase inhibitor stefin A, STF1, to chromosome 3cen-q21.

Authors:  W T Hsieh; D Fong; B F Sloane; W Golembieski; D I Smith
Journal:  Genomics       Date:  1991-01       Impact factor: 5.736

7.  Hereditary spherocytosis associated with deletion of human erythrocyte ankyrin gene on chromosome 8.

Authors:  S E Lux; W T Tse; J C Menninger; K M John; P Harris; O Shalev; R R Chilcote; S L Marchesi; P C Watkins; V Bennett
Journal:  Nature       Date:  1990-06-21       Impact factor: 49.962

8.  Assignment of cathepsin E (CTSE) to human chromosome region 1q31 by in situ hybridization and analysis of somatic cell hybrids.

Authors:  J M Couvreur; T Azuma; D A Miller; M Rocchi; T K Mohandas; F A Boudi; R T Taggart
Journal:  Cytogenet Cell Genet       Date:  1990

9.  Enhanced levels of cathepsin B mRNA in murine tumors.

Authors:  K Moin; J Rozhin; T B McKernan; V J Sanders; D Fong; K V Honn; B F Sloane
Journal:  FEBS Lett       Date:  1989-02-13       Impact factor: 4.124

10.  A cluster of hematopoietic serine protease genes is found on the same chromosomal band as the human alpha/delta T-cell receptor locus.

Authors:  R D Hanson; P A Hohn; N C Popescu; T J Ley
Journal:  Proc Natl Acad Sci U S A       Date:  1990-02       Impact factor: 11.205
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  9 in total

1.  The genes of the lysosomal cysteine proteinases cathepsin B, H, L, and S map to different mouse chromosomes.

Authors:  J Deussing; W Roth; W Rommerskirch; B Wiederanders; K von Figura; C Peters
Journal:  Mamm Genome       Date:  1997-04       Impact factor: 2.957

Review 2.  Cathepsin B as a cancer target.

Authors:  Christopher S Gondi; Jasti S Rao
Journal:  Expert Opin Ther Targets       Date:  2013-01-08       Impact factor: 6.902

3.  Cathepsin B: Basis Sequence: Mouse.

Authors:  Dora Cavallo-Medved; Kamiar Moin; Bonnie Sloane
Journal:  AFCS Nat Mol Pages       Date:  2011-04-10

4.  Genetic and physical mapping of the progressive epilepsy with mental retardation (EPMR) locus on chromosome 8p.

Authors:  S Ranta; A E Lehesjoki; A Hirvasniemi; J Weissenbach; B Ross; S M Leal; A de la Chapelle; T C Gilliam
Journal:  Genome Res       Date:  1996-05       Impact factor: 9.043

Review 5.  Cathepsin B Gene Knockout Improves Behavioral Deficits and Reduces Pathology in Models of Neurologic Disorders.

Authors:  Gregory Hook; Thomas Reinheckel; Junjun Ni; Zhou Wu; Mark Kindy; Christoph Peters; Vivian Hook
Journal:  Pharmacol Rev       Date:  2022-07       Impact factor: 18.923

6.  The gene for a recessively inherited human childhood progressive epilepsy with mental retardation maps to the distal short arm of chromosome 8.

Authors:  E Tahvanainen; S Ranta; A Hirvasniemi; E Karila; J Leisti; P Sistonen; J Weissenbach; A E Lehesjoki; A de la Chapelle
Journal:  Proc Natl Acad Sci U S A       Date:  1994-07-19       Impact factor: 11.205

Review 7.  Cathepsins mediate tumor metastasis.

Authors:  Gong-Jun Tan; Zheng-Ke Peng; Jin-Ping Lu; Fa-Qing Tang
Journal:  World J Biol Chem       Date:  2013-11-26

8.  Genomic divergences among cattle, dog and human estimated from large-scale alignments of genomic sequences.

Authors:  George E Liu; Lakshmi K Matukumalli; Tad S Sonstegard; Larry L Shade; Curtis P Van Tassell
Journal:  BMC Genomics       Date:  2006-06-07       Impact factor: 3.969

Review 9.  Cathepsin B is a New Drug Target for Traumatic Brain Injury Therapeutics: Evidence for E64d as a Promising Lead Drug Candidate.

Authors:  Gregory Hook; J Steven Jacobsen; Kenneth Grabstein; Mark Kindy; Vivian Hook
Journal:  Front Neurol       Date:  2015-09-02       Impact factor: 4.003
  9 in total

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