| Literature DB >> 15773061 |
Shun-ichiro Ogura1, Keiko Yazaki, Kazuki Yamaguchi, Toshiaki Kamachi, Ichiro Okura.
Abstract
The cellular uptake and photocytotoxity of poly-l-lysine (pL)-chlorin e6 (Ce6) conjugate were investigated. The cellularuptake of pL-Ce6 conjugate for HeLa cells was much higher than that of Ce6, and pL-Ce6 conjugate had high binding affinityfor HeLa cells. pL-Ce6 conjugate was accumulated in the nucleus of HeLa cells, and the effective photocytotoxity wasobserved by the irradiation.Entities:
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Year: 2005 PMID： 15773061 DOI： 10.1016/j.jconrel.2004.11.010
Source DB: PubMed Journal: J Control Release ISSN： 0168-3659 Impact factor: 9.776