Literature DB >> 15770550

Cytotoxic and antifungal isoprenylated xanthones and flavonoids from Cudrania fruticosa.

Yong-Hong Wang1, Ai-Jun Hou, Guo-Fu Zhu, Dao-Feng Chen, Han-Dong Sun.   

Abstract

A new isoprenylated xanthone, cudrafrutixanthone A, was isolated from the roots of Cudrania fruticosa, together with 18 known compounds. Their structures were elucidated by spectroscopic methods. Most isoprenylated xanthones exhibited cytotoxicity against HCT-116, SMMC-7721, SGC-7901, and BGC-823 cell lines with IC (50) values of 1 - 5 microg/mL. Toxyloxanthone C and wighteone showed antifungal activity against Candida albicans with MICs of 25 and 12.5 microg/mL, respectively.

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Year:  2005        PMID: 15770550     DOI: 10.1055/s-2005-837829

Source DB:  PubMed          Journal:  Planta Med        ISSN: 0032-0943            Impact factor:   3.352


  2 in total

1.  Alvaxanthone, a Thymidylate Synthase Inhibitor with Nematocidal and Tumoricidal Activities.

Authors:  Piotr Maj; Mattia Mori; Justyna Sobich; Joanna Markowicz; Łukasz Uram; Zbigniew Zieliński; Deborah Quaglio; Andrea Calcaterra; Ylenia Cau; Bruno Botta; Wojciech Rode
Journal:  Molecules       Date:  2020-06-23       Impact factor: 4.411

2.  UPLC-ESI-Q-TOF-MS-Based Metabolite Profiling, Antioxidant and Anti-Inflammatory Properties of Different Organ Extracts of Abeliophyllum distichum.

Authors:  Tong-Kewn Yoo; Won Tae Jeong; Jun Gu Kim; Hyo Seong Ji; Min-A Ahn; Jong-Wook Chung; Heung Bin Lim; Tae Kyung Hyun
Journal:  Antioxidants (Basel)       Date:  2021-01-07
  2 in total

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