Literature DB >> 15770417

Leptin receptor action and mechanisms of leptin resistance.

H Münzberg1, M Björnholm, S H Bates, M G Myers.   

Abstract

The adipose tissue-derived hormone leptin regulates energy balance and neuroendocrine function. Resistance to the appetite-suppressing effects of leptin is associated with common forms of obesity. Here, we review the mechanisms by which leptin activates intracellular signals and the roles that these signals play in leptin action in vivo. Furthermore, we discuss potential mechanisms of leptin resistance, specifically focusing on data regarding the neuroanatomical locus of leptin resistance and potential mechanisms by which expression of the suppressor of cytokine signaling-3 may impair leptin action.

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Year:  2005        PMID： 15770417     DOI： 10.1007/s00018-004-4432-1

Source DB:  PubMed          Journal:  Cell Mol Life Sci        ISSN： 1420-682X            Impact factor:   9.261


  31 in total

1.  Percutaneous closure of patent foramen ovale: impact of device design on safety and efficacy.

Authors:  M Schwerzmann; S Windecker; A Wahl; H Mehta; K Nedeltchev; H Mattle; C Seiler; B Meier
Journal:  Heart       Date:  2004-02       Impact factor: 5.994

2.  Patent foramen ovale closure vs medical therapy for stroke prevention: meta-analysis of randomized trials and review of heterogeneity in meta-analyses.

Authors:  Jacob A Udell; Alexander R Opotowsky; Paul Khairy; Candice K Silversides; David J Gladstone; Patrick T O'Gara; Michael J Landzberg
Journal:  Can J Cardiol       Date:  2014-05-09       Impact factor: 5.223

Review 3.  Stroke prevention by percutaneous closure of patent foramen ovale: a systematic review and meta-analysis.

Authors:  Mathias Wolfrum; Georg M Froehlich; Guido Knapp; Leanne K Casaubon; James J DiNicolantonio; Alexandra J Lansky; Pascal Meier
Journal:  Heart       Date:  2013-06-21       Impact factor: 5.994

4.  Closure or medical therapy for cryptogenic stroke with patent foramen ovale.

Authors:  Anthony J Furlan; Mark Reisman; Joseph Massaro; Laura Mauri; Harold Adams; Gregory W Albers; Robert Felberg; Howard Herrmann; Saibal Kar; Michael Landzberg; Albert Raizner; Lawrence Wechsler
Journal:  N Engl J Med       Date:  2012-03-15       Impact factor: 91.245

5.  Percutaneous closure of patent foramen ovale for cryptogenic stroke: a meta-analysis of randomized controlled trials.

Authors:  Joey S W Kwong; Yat-Yin Lam; Cheuk-Man Yu
Journal:  Int J Cardiol       Date:  2013-07-24       Impact factor: 4.164

6.  Comparison of three patent foramen ovale closure devices in a randomized trial (Amplatzer versus CardioSEAL-STARflex versus Helex occluder).

Authors:  Margaret Taaffe; Evelyn Fischer; Andreas Baranowski; Nicolas Majunke; Corinna Heinisch; Michaela Leetz; Ralph Hein; Yves Bayard; Franziska Büscheck; Madlen Reschke; Ilona Hoffmann; Nina Wunderlich; Neil Wilson; Horst Sievert
Journal:  Am J Cardiol       Date:  2008-03-10       Impact factor: 2.778

Review 7.  Patent foramen ovale transcatheter closure vs. medical therapy on recurrent vascular events: a systematic review and meta-analysis of randomized controlled trials.

Authors:  Pablo Rengifo-Moreno; Igor F Palacios; Parichart Junpaparp; Christian F Witzke; D Lynn Morris; Abel Romero-Corral
Journal:  Eur Heart J       Date:  2013-07-11       Impact factor: 29.983

8.  Closure of patent foramen ovale versus medical therapy after cryptogenic stroke.

Authors:  John D Carroll; Jeffrey L Saver; David E Thaler; Richard W Smalling; Scott Berry; Lee A MacDonald; David S Marks; David L Tirschwell
Journal:  N Engl J Med       Date:  2013-03-21       Impact factor: 91.245

Review 9.  Updating the evidence on patent foramen ovale closure versus medical therapy in patients with cryptogenic stroke: a systematic review and comprehensive meta-analysis of 2,303 patients from three randomised trials and 2,231 patients from 11 observational studies.

Authors:  Davide Capodanno; Giovanni Milazzo; Luca Vitale; Daniele Di Stefano; Marilena Di Salvo; Carmelo Grasso; Corrado Tamburino
Journal:  EuroIntervention       Date:  2014-03-20       Impact factor: 6.534

Review 10.  Systematic review of percutaneous closure versus medical therapy in patients with cryptogenic stroke and patent foramen ovale.

Authors:  Frederick A Spencer; Luciane C Lopes; Sean A Kennedy; Gordon Guyatt
Journal:  BMJ Open       Date:  2014-03-07       Impact factor: 2.692
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  61 in total

Review 1.  Cognitive and neuronal systems underlying obesity.

Authors:  Scott E Kanoski
Journal:  Physiol Behav       Date:  2012-01-12

2.  Leptin receptor JAK2/STAT3 signaling modulates expression of Frizzled receptors in articular chondrocytes.

Authors:  S Ohba; T M Lanigan; B J Roessler
Journal:  Osteoarthritis Cartilage       Date:  2010-09-22       Impact factor: 6.576

Review 3.  Leptin signalling pathways in hypothalamic neurons.

Authors:  Obin Kwon; Ki Woo Kim; Min-Seon Kim
Journal:  Cell Mol Life Sci       Date:  2016-01-19       Impact factor: 9.261

4.  Respiratory responses to microinjections of leptin into the solitary tract nucleus.

Authors:  A N Inyushkin; E M Inyushkina; N A Merkulova
Journal:  Neurosci Behav Physiol       Date:  2009-02-21

5.  Phenotypic effects of an induced mutation of the ObRa isoform of the leptin receptor.

Authors:  Zhiying Li; Giovanni Ceccarini; Michael Eisenstein; Keith Tan; Jeffrey Michael Friedman
Journal:  Mol Metab       Date:  2013-08-04       Impact factor: 7.422

6.  Modulation of AgRP-neuronal function by SOCS3 as an initiating event in diet-induced hypothalamic leptin resistance.

Authors:  Louise E Olofsson; Elizabeth K Unger; Clement C Cheung; Allison W Xu
Journal:  Proc Natl Acad Sci U S A       Date:  2013-02-05       Impact factor: 11.205

7.  Beyond thermoregulation: metabolic function of cetacean blubber in migrating bowhead and beluga whales.

Authors:  H C Ball; R L Londraville; J W Prokop; John C George; R S Suydam; C Vinyard; J G M Thewissen; R J Duff
Journal:  J Comp Physiol B       Date:  2016-08-29       Impact factor: 2.200

8.  Leptin and the control of pharyngeal patency during sleep in severe obesity.

Authors:  Steven D Shapiro; Chien-Hung Chin; Jason P Kirkness; Brian M McGinley; Susheel P Patil; Vsevolod Y Polotsky; Paolo Jose Cesare Biselli; Philip L Smith; Hartmut Schneider; Alan R Schwartz
Journal:  J Appl Physiol (1985)       Date:  2014-02-20

9.  Inflammation status of rabbit carotid artery model endothelium during intermittent hypoxia exposure and its relationship with leptin.

Authors:  Jing Feng; Bao-yuan Chen; Lin-yang Cui; Bao-li Wang; Chun-xia Liu; Pan-feng Chen; Mei-nan Guo; Li-xia Dong; Shuo Li
Journal:  Sleep Breath       Date:  2009-03-17       Impact factor: 2.816

10.  Leptin signaling: A key pathway in immune responses.

Authors:  Claudio Procaccini; Elaine V Lourenco; Giuseppe Matarese; Antonio La Cava
Journal:  Curr Signal Transduct Ther       Date:  2009-01-01
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