Literature DB >> 1577041

Enantioselective pharmacodynamics and pharmacokinetics of chiral non-steroidal anti-inflammatory drugs.

A M Evans1.   

Abstract

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Year:  1992        PMID： 1577041     DOI： 10.1007/bf00266343

Source DB:  PubMed          Journal:  Eur J Clin Pharmacol        ISSN： 0031-6970            Impact factor:   2.953


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  130 in total

Review 1.  Pharmacokinetic drug interactions with nonsteroidal anti-inflammatory drugs.

Authors:  R K Verbeeck
Journal:  Clin Pharmacokinet       Date:  1990-07       Impact factor: 6.447

2.  Inversion of optical configuration of alpha-methylfluorene-2-acetic acid (cicloprofen) in rats and monkeys.

Authors:  S J Lan; K J Kripalani; A V Dean; P Egli; L T Difazio; E C Schreiber
Journal:  Drug Metab Dispos       Date:  1976 Jul-Aug       Impact factor: 3.922

3.  Suppression of inflammatory oedema by ibuprofen involving a mechanism independent of cyclo-oxygenase inhibition.

Authors:  M Rampart; T J Williams
Journal:  Biochem Pharmacol       Date:  1986-02-15       Impact factor: 5.858

Review 4.  Interrelationships between xenobiotic metabolism and lipid biosynthesis.

Authors:  J Caldwell; M V Marsh
Journal:  Biochem Pharmacol       Date:  1983-06-01       Impact factor: 5.858

5.  The pharmacokinetics of the enantiomers of flurbiprofen in patients with rheumatoid arthritis.

Authors:  M A Young; L Aarons; S Toon
Journal:  Br J Clin Pharmacol       Date:  1991-01       Impact factor: 4.335

6.  Pharmacokinetics of ketoprofen enantiomers in cholecystectomy patients: influence of probenecid.

Authors:  R T Foster; F Jamali; A S Russell
Journal:  Eur J Clin Pharmacol       Date:  1989       Impact factor: 2.953

7.  Metabolic chiral inversion of anti-inflammatory 2-arylpropionates: lack of reaction in liver homogenates, and study of methine proton acidity.

Authors:  J M Mayer; C Bartolucci; J M Maître; B Testa
Journal:  Xenobiotica       Date:  1988-05       Impact factor: 1.908

8.  Inhibition of prostaglandin biosynthesis by clidanac and related compounds: structural and conformational requirements for PG synthetase inhibition.

Authors:  S Tamura; S Kuzuna; K Kawai
Journal:  J Pharm Pharmacol       Date:  1981-01       Impact factor: 3.765

9.  Effect of racemic ibuprofen dose on the magnitude and duration of platelet cyclo-oxygenase inhibition: relationship between inhibition of thromboxane production and the plasma unbound concentration of S(+)-ibuprofen.

Authors:  A M Evans; R L Nation; L N Sansom; F Bochner; A A Somogyi
Journal:  Br J Clin Pharmacol       Date:  1991-02       Impact factor: 4.335

10.  A model for the prostaglandin synthetase cyclooxygenation site and its inhibition by antiinflammatory arylacetic acids.

Authors:  P Gund; T Y Shen
Journal:  J Med Chem       Date:  1977-09       Impact factor: 7.446
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  37 in total

Review 1.  Choosing the right nonsteroidal anti-inflammatory drug for the right patient: a pharmacokinetic approach.

Authors:  N M Davies; N M Skjodt
Journal:  Clin Pharmacokinet       Date:  2000-05       Impact factor: 6.447

Review 2.  Do the pharmacodynamics of the nonsteroidal anti-inflammatory drugs suggest a role in the management of postoperative pain?

Authors:  L E Mather
Journal:  Drugs       Date:  1992       Impact factor: 9.546

3.  Chirality and drugs used to treat psychiatric disorders.

Authors:  Glen B Baker; Trevor I Prior; Ronald T Coutts
Journal:  J Psychiatry Neurosci       Date:  2002-11       Impact factor: 6.186

4.  Effects of the antifungals voriconazole and fluconazole on the pharmacokinetics of s-(+)- and R-(-)-Ibuprofen.

Authors:  Ville-Veikko Hynninen; Klaus T Olkkola; Kari Leino; Stefan Lundgren; Pertti J Neuvonen; Anders Rane; Mika Valtonen; Hanna Vyyryläinen; Kari Laine
Journal:  Antimicrob Agents Chemother       Date:  2006-06       Impact factor: 5.191

Review 5.  Chirality and nonsteroidal anti-inflammatory drugs.

Authors:  P J Hayball
Journal:  Drugs       Date:  1996       Impact factor: 9.546

Review 6.  Drug chirality and its clinical significance.

Authors:  A J Hutt; S C Tan
Journal:  Drugs       Date:  1996       Impact factor: 9.546

7.  Enantiomers of flurbiprofen can distinguish key pathophysiological steps of NSAID enteropathy in the rat.

Authors:  T Mahmud; S Somasundaram; G Sigthorsson; R J Simpson; S Rafi; R Foster; I A Tavares; A Roseth; A J Hutt; M Jacob; J Pacy; D L Scott; J M Wrigglesworth; I Bjarnason
Journal:  Gut       Date:  1998-12       Impact factor: 23.059

8.  Stereoselective flunoxaprofen-S-acyl-glutathione thioester formation mediated by acyl-CoA formation in rat hepatocytes.

Authors:  Mark P Grillo; Jill C M Wait; Michelle Tadano Lohr; Smriti Khera; Leslie Z Benet
Journal:  Drug Metab Dispos       Date:  2010-01       Impact factor: 3.922

9.  Disposition of ibuprofen in patients with liver cirrhosis. Stereochemical considerations.

Authors:  G Li; G Treiber; K Maier; S Walker; U Klotz
Journal:  Clin Pharmacokinet       Date:  1993-08       Impact factor: 6.447

10.  Cytochrome P450 2C8 pharmacogenetics: a review of clinical studies.

Authors:  Elizabeth B Daily; Christina L Aquilante
Journal:  Pharmacogenomics       Date:  2009-09       Impact factor: 2.533
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