| Literature DB >> 15770092 |
Ling Ma1, Feng-Yee Chang, Chang-Phone Fung, Te-Li Chen, Jung-Chung Lin, Po-Liang Lu, Li-Yueh Huang, Jen-Chang Chang, L K Siu.
Abstract
A total of 171 hospitals' isolates of E. coli, K. pneumoniae, and E. cloacae with a minimum inhibitory concentration (MIC) of > or =2 microg/ml for ceftazidime or cefotaxime were evaluated for the production of beta-lactamases. PCR amplification with specific primers for the bla (SHV), bla (TEM), and bla (CTX) genes revealed that a total of 53, 81, and 43 of these genes were amplified, respectively. Sequencing results confirmed that TEM-1, CTX-M-3 and -14, SHV-1, -5, -11, -12, and -33, OXY-1a, and LEN-1 were presented among these isolates. No specific large cluster of isolates carried the same beta-lactamases, indicating the wide diversity of the collected strains. Plasmid spread between E. coli and K. pneumoniae was identified in few isolates. Combinations of TEM, SHV, and CTX beta-lactamase genes, including extended-spectrum beta-lactamase genes, were observed in all three species.Entities:
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Year: 2005 PMID： 15770092 DOI： 10.1089/mdr.2005.11.31
Source DB: PubMed Journal: Microb Drug Resist ISSN： 1076-6294 Impact factor: 3.431