Literature DB >> 15768564

Clinical results of Perftoran application: present and future.

Eugene Maevsky1, Genrih Ivanitsky, Ludmila Bogdanova, Olga Axenova, Natalia Karmen, Eugene Zhiburt, Raisa Senina, Sergey Pushkin, Igor Maslennikov, Andrey Orlov, Irina Marinicheva.   

Abstract

Clinical experience of Perftoran (commercial drug of low concentrated perfluorocheminal emulsion) applications is presented in some statistical data and in brief analysis of clinical trials and following clinical studies described in the Russian scientific literature. Observed data allow us to suppose that Perftoran facilitates oxygen delivery together with remaining red blood cells at blood replacements and will have more wider area for application than just a blood substitute. Its infusion alleviates symptoms of ischemia at different types of occlusion vessels disease, improves grafting in plastic surgery, diminishes inflammation and prevents rejection of transplants, activates detoxication functions of liver, inhibits retro-virus infection development. Local PF applications is able to accelerate wounds and ulcers healing.

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Year:  2005        PMID: 15768564     DOI: 10.1081/bio-200046654

Source DB:  PubMed          Journal:  Artif Cells Blood Substit Immobil Biotechnol        ISSN: 1073-1199


  13 in total

1.  Spanish Consensus Statement on alternatives to allogeneic blood transfusion: the 2013 update of the "Seville Document".

Authors:  Santiago R Leal-Noval; Manuel Muñoz; Marisol Asuero; Enric Contreras; José A García-Erce; Juan V Llau; Victoria Moral; José A Páramo; Manuel Quintana
Journal:  Blood Transfus       Date:  2013-06-17       Impact factor: 3.443

2.  In vivo MRI virtual colonography in a mouse model of colon cancer.

Authors:  Lilia V Ileva; Marcelino Bernardo; Matthew R Young; Lisa A Riffle; James L Tatum; Joseph D Kalen; Peter L Choyke
Journal:  Nat Protoc       Date:  2014-10-23       Impact factor: 13.491

3.  Perfluorocarbon nanoparticle-mediated platelet inhibition promotes intratumoral infiltration of T cells and boosts immunotherapy.

Authors:  Zaigang Zhou; Baoli Zhang; Wenjing Zai; Lin Kang; Ahu Yuan; Yiqiao Hu; Jinhui Wu
Journal:  Proc Natl Acad Sci U S A       Date:  2019-05-29       Impact factor: 11.205

Review 4.  Bio-inspired nanomedicine strategies for artificial blood components.

Authors:  Anirban Sen Gupta
Journal:  Wiley Interdiscip Rev Nanomed Nanobiotechnol       Date:  2017-03-15

Review 5.  [Artificial oxygen carriers as an alternative to red blood cell transfusion].

Authors:  O Habler; A Pape; J Meier; B Zwissler
Journal:  Anaesthesist       Date:  2005-08       Impact factor: 1.041

Review 6.  Nanotechnology as a Versatile Tool for 19F-MRI Agent's Formulation: A Glimpse into the Use of Perfluorinated and Fluorinated Compounds in Nanoparticles.

Authors:  Joice Maria Joseph; Maria Rosa Gigliobianco; Bita Mahdavi Firouzabadi; Roberta Censi; Piera Di Martino
Journal:  Pharmaceutics       Date:  2022-02-09       Impact factor: 6.321

7.  Enhancement of radiotherapy efficacy by pleiotropic liposomes encapsulated paclitaxel and perfluorotributylamine.

Authors:  Xing Jiang; Baoli Zhang; Zaigang Zhou; Lingtong Meng; Zhiling Sun; Yun Xu; Qiuping Xu; Ahu Yuan; Lixia Yu; Hanqing Qian; Jinhui Wu; Yiqiao Hu; Baorui Liu
Journal:  Drug Deliv       Date:  2017-11       Impact factor: 6.419

Review 8.  Increasing Superoxide Production and the Labile Iron Pool in Tumor Cells may Sensitize Them to Extracellular Ascorbate.

Authors:  Mark Frederick McCarty; Francisco Contreras
Journal:  Front Oncol       Date:  2014-09-16       Impact factor: 6.244

9.  Cerebral Microvascular and Systemic Effects Following Intravenous Administration of the Perfluorocarbon Emulsion Perftoran.

Authors:  Rania Abutarboush; Biswajit K Saha; Saad H Mullah; Francoise G Arnaud; Ashraful Haque; Chioma Aligbe; Georgina Pappas; Charles R Auker; Richard M McCarron; Paula F Moon-Massat; Anke H Scultetus
Journal:  J Funct Biomater       Date:  2016-11-18

Review 10.  Probing the Electrophysiology of the Developing Heart.

Authors:  Michiko Watanabe; Andrew M Rollins; Luis Polo-Parada; Pei Ma; Shi Gu; Michael W Jenkins
Journal:  J Cardiovasc Dev Dis       Date:  2016-03-22
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