Literature DB >> 15768334

Role of liver biopsy in the evaluation of hepatitis C virus infection in HIV coinfection.

Richard K Sterling1.   

Abstract

Hepatitis C virus (HCV) coinfection is common in patients infected with human immunodeficiency virus (HIV), because the viruses share common routes of transmission. With the marked increase in life expectancy of HIV-infected patients associated with the use of highly active antiretroviral therapy, HCV infection has become a significant cause of morbidity and mortality in coinfected patients. As a result, there has been increasing attention to adequate assessment of HCV infection during the last several years. Unlike liver enzymes and HCV RNA levels, which can fluctuate widely and do not correlate with the severity of disease, liver biopsy has become the cornerstone in the evaluation of chronic HCV infection. However, there remain important questions and controversies related to adequately determining the histological severity of liver disease and the role of liver biopsy in HIV-HCV-coinfected patients.

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Year:  2005        PMID: 15768334     DOI: 10.1086/427439

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN: 1058-4838            Impact factor:   9.079


  5 in total

1.  Similar progression of fibrosis between HIV/HCV-infected and HCV-infected patients: Analysis of paired liver biopsy samples.

Authors:  Richard K Sterling; Jacob A Wegelin; Paula G Smith; R Todd Stravitz; Velimir A Luketic; Michael Fuchs; Puneet Puri; Mitchell L Shiffman; Melissa A Contos; A Scott Mills; Arun J Sanyal
Journal:  Clin Gastroenterol Hepatol       Date:  2010-08-20       Impact factor: 11.382

Review 2.  Hepatitis infection in the treatment of opioid dependence and abuse.

Authors:  Thomas F Kresina; Diana Sylvestre; Leonard Seeff; Alain H Litwin; Kenneth Hoffman; Robert Lubran; H Westley Clark
Journal:  Subst Abuse       Date:  2008-04-28

3.  HIV coinfection with hepatitis C and hepatitis B.

Authors:  Jenny O Smith; Richard K Sterling
Journal:  Curr Infect Dis Rep       Date:  2006-09       Impact factor: 3.725

4.  HIV-HCV Coinfection.

Authors:  Amrita Sethi; Richard K Sterling
Journal:  Gastroenterol Hepatol (N Y)       Date:  2006-05

Review 5.  Hepatitis C and HIV.

Authors:  Jenny O Smith; Richard K Sterling
Journal:  Curr Gastroenterol Rep       Date:  2007-03
  5 in total

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