Literature DB >> 15766228

Bone morphogenetic proteins: basic concepts.

Setti S Rengachary1.   

Abstract

The cellular and molecular events governing bone formation in the embryo, healing of a fractured bone, and induced bone fusion follow a similar pattern. Discovery, purification, and recombinant synthesis of bone morphogenetic proteins (BMPs) constitute a major milestone in the understanding of bone physiology. In this review the author discusses the mechanism of action, clinical applications, dosage, and optimum carriers for BMPs. The roles played by other growth factors are also discussed.

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Year:  2002        PMID： 15766228     DOI： 10.3171/foc.2002.13.6.3

Source DB:  PubMed          Journal:  Neurosurg Focus        ISSN： 1092-0684            Impact factor:   4.047


  16 in total

1.  Covalent binding of BMP-2 on surfaces using a self-assembled monolayer approach.

Authors:  Theresa L M Pohl; Elisabeth H Schwab; Elisabetta A Cavalcanti-Adam
Journal:  J Vis Exp       Date:  2013-08-26       Impact factor: 1.355

Review 2.  Current status of bone graft options for anterior interbody fusion of the cervical and lumbar spine.

Authors:  Anthony Minh Tien Chau; Lileane Liang Xu; Johnny Ho-Yin Wong; Ralph Jasper Mobbs
Journal:  Neurosurg Rev       Date:  2013-06-07       Impact factor: 3.042

3.  Are endogenous BMPs necessary for bone healing during distraction osteogenesis?

Authors:  Norine Alam; René St-Arnaud; Dominique Lauzier; Vicki Rosen; Reggie C Hamdy
Journal:  Clin Orthop Relat Res       Date:  2009-12       Impact factor: 4.176

Review 4.  BMP-2-induced bone formation and neural inflammation.

Authors:  Vi Nguyen; Carolyn A Meyers; Noah Yan; Shailesh Agarwal; Benjamin Levi; Aaron W James
Journal:  J Orthop       Date:  2017-03-20

5.  Enhanced Mandibular Bone Repair by Combined Treatment of Bone Morphogenetic Protein 2 and Small-Molecule Phenamil.

Authors:  Jiabing Fan; Mian Guo; Choong Sung Im; Joan Pi-Anfruns; Zhong-Kai Cui; Soyon Kim; Benjamin M Wu; Tara L Aghaloo; Min Lee
Journal:  Tissue Eng Part A       Date:  2016-11-28       Impact factor: 3.845

Review 6.  A Review of the Clinical Side Effects of Bone Morphogenetic Protein-2.

Authors:  Aaron W James; Gregory LaChaud; Jia Shen; Greg Asatrian; Vi Nguyen; Xinli Zhang; Kang Ting; Chia Soo
Journal:  Tissue Eng Part B Rev       Date:  2016-04-19       Impact factor: 6.389

7.  Osteogenic protein-1 for long bone nonunion: an evidence-based analysis.

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Journal:  Ont Health Technol Assess Ser       Date:  2005-04-01

8.  Characterization and expression of bone morphogenetic protein 4 gene in postnatal pigs.

Authors:  Ming Li; Qixin Chen; Guirong Sun; Xiaowei Shi; Qiaohui Zhao; Chi Zhang; Jianshe Zhou; Nan Qin
Journal:  Mol Biol Rep       Date:  2009-08-18       Impact factor: 2.316

9.  A differential effect of bone morphogenetic protein-2 and vascular endothelial growth factor release timing on osteogenesis at ectopic and orthotopic sites in a large-animal model.

Authors:  Ruth E Geuze; Lars F H Theyse; Diederik H R Kempen; Herman A W Hazewinkel; Helen Y A Kraak; F Cumhur Oner; Wouter J A Dhert; Jacqueline Alblas
Journal:  Tissue Eng Part A       Date:  2012-09-12       Impact factor: 3.845

10.  The effect of heparan sulfate application on bone formation during distraction osteogenesis.

Authors:  Marie Gdalevitch; Bahar Kasaai; Norine Alam; Bruno Dohin; Dominique Lauzier; Reggie C Hamdy
Journal:  PLoS One       Date:  2013-02-15       Impact factor: 3.240
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