Literature DB >> 15764650

How many states can the motor molecule, prestin, assume in an electric field?

Marc P Scherer1, Anthony W Gummer.   

Abstract

By using an analogy between the magnetization of a paramagnetic material in an external magnetic field and the electric polarization of the lateral wall of outer hair cells in response to the transmembrane potential, we show that, based on experimental data on the charge transfer across the membrane, it is impossible to make a statement about the number of possible conformational states of the motor molecule, prestin. Although the choice of model affects the values of derived parameters, such as total charge and motor charge, this is frequently overlooked in the literature.

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Year:  2005        PMID: 15764650      PMCID: PMC1305522          DOI: 10.1529/biophysj.105.059782

Source DB:  PubMed          Journal:  Biophys J        ISSN: 0006-3495            Impact factor:   4.033


  14 in total

1.  A membrane bending model of outer hair cell electromotility.

Authors:  R M Raphael; A S Popel; W E Brownell
Journal:  Biophys J       Date:  2000-06       Impact factor: 4.033

2.  Voltage-dependent changes in specific membrane capacitance caused by prestin, the outer hair cell lateral membrane motor.

Authors:  Joseph Santos-Sacchi; Enrique Navarrete
Journal:  Pflugers Arch       Date:  2002-02-20       Impact factor: 3.657

3.  Intracellular anions as the voltage sensor of prestin, the outer hair cell motor protein.

Authors:  D Oliver; D Z He; N Klöcker; J Ludwig; U Schulte; S Waldegger; J P Ruppersberg; P Dallos; B Fakler
Journal:  Science       Date:  2001-06-22       Impact factor: 47.728

4.  A two-state piezoelectric model for outer hair cell motility.

Authors:  K H Iwasa
Journal:  Biophys J       Date:  2001-11       Impact factor: 4.033

5.  Limiting dynamics of high-frequency electromechanical transduction of outer hair cells.

Authors:  G Frank; W Hemmert; A W Gummer
Journal:  Proc Natl Acad Sci U S A       Date:  1999-04-13       Impact factor: 11.205

6.  Prestin is the motor protein of cochlear outer hair cells.

Authors:  J Zheng; W Shen; D Z He; K B Long; L D Madison; P Dallos
Journal:  Nature       Date:  2000-05-11       Impact factor: 49.962

7.  Theory of electrically driven shape changes of cochlear outer hair cells.

Authors:  P Dallos; R Hallworth; B N Evans
Journal:  J Neurophysiol       Date:  1993-07       Impact factor: 2.714

8.  A model for signal transmission in an ear having hair cells with free-standing stereocilia. IV. Mechanoelectric transduction stage.

Authors:  T F Weiss; R Leong
Journal:  Hear Res       Date:  1985       Impact factor: 3.208

9.  Prestin is required for electromotility of the outer hair cell and for the cochlear amplifier.

Authors:  M Charles Liberman; Jiangang Gao; David Z Z He; Xudong Wu; Shuping Jia; Jian Zuo
Journal:  Nature       Date:  2002-08-28       Impact factor: 49.962

10.  Reversible inhibition of voltage-dependent outer hair cell motility and capacitance.

Authors:  J Santos-Sacchi
Journal:  J Neurosci       Date:  1991-10       Impact factor: 6.167

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  9 in total

1.  Evidence that prestin has at least two voltage-dependent steps.

Authors:  Kazuaki Homma; Peter Dallos
Journal:  J Biol Chem       Date:  2010-11-11       Impact factor: 5.157

Review 2.  Electromechanical models of the outer hair cell composite membrane.

Authors:  A A Spector; N Deo; K Grosh; J T Ratnanather; R M Raphael
Journal:  J Membr Biol       Date:  2006-05-25       Impact factor: 1.843

3.  A virtual hair cell, I: addition of gating spring theory into a 3-D bundle mechanical model.

Authors:  Jong-Hoon Nam; John R Cotton; Wally Grant
Journal:  Biophys J       Date:  2007-01-05       Impact factor: 4.033

4.  Effects of chlorpromazine and trinitrophenol on the membrane motor of outer hair cells.

Authors:  Jie Fang; K H Iwasa
Journal:  Biophys J       Date:  2007-05-04       Impact factor: 4.033

5.  Chloride Anions Regulate Kinetics but Not Voltage-Sensor Qmax of the Solute Carrier SLC26a5.

Authors:  Joseph Santos-Sacchi; Lei Song
Journal:  Biophys J       Date:  2016-06-07       Impact factor: 4.033

6.  Disparities in voltage-sensor charge and electromotility imply slow chloride-driven state transitions in the solute carrier SLC26a5.

Authors:  Lei Song; Joseph Santos-Sacchi
Journal:  Proc Natl Acad Sci U S A       Date:  2013-02-19       Impact factor: 11.205

7.  Prestin surface expression and activity are augmented by interaction with MAP1S, a microtubule-associated protein.

Authors:  Jun-Ping Bai; Alexei Surguchev; Yudelca Ogando; Lei Song; Shumin Bian; Joseph Santos-Sacchi; Dhasakumar Navaratnam
Journal:  J Biol Chem       Date:  2010-04-23       Impact factor: 5.157

8.  Voltage and frequency dependence of prestin-associated charge transfer.

Authors:  Sean X Sun; Brenda Farrell; Matthew S Chana; George Oster; William E Brownell; Alexander A Spector
Journal:  J Theor Biol       Date:  2009-05-31       Impact factor: 2.691

9.  Prestin's anion transport and voltage-sensing capabilities are independent.

Authors:  Jun-Ping Bai; Alexei Surguchev; Simone Montoya; Peter S Aronson; Joseph Santos-Sacchi; Dhasakumar Navaratnam
Journal:  Biophys J       Date:  2009-04-22       Impact factor: 4.033

  9 in total

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