| Literature DB >> 15763598 |
Agnieszka Bartmańska1, Jadwiga Dmochowska-Gładysz, Ewa Huszcza.
Abstract
The application of Penicillium notatum genus for biotransformations of steroids has been investigated. The reactions observed include insertion of an oxygen atom into D-ring of steroids, 15alpha-hydroxylation of 17alpha-methyl testosterone derivatives, ester bond hydrolysis, and degradation of a testosterone derivatives side chain. Microbial production of testolactones, the biologically active compounds, was also achieved using this strain in up to 98% yield.Entities:
Mesh：
Substances：
Year: 2005 PMID： 15763598 DOI： 10.1016/j.steroids.2004.11.011
Source DB: PubMed Journal: Steroids ISSN： 0039-128X Impact factor: 2.668