BACKGROUND: Patients with basal cell carcinoma (BCC) frequently develop further tumors during follow-up. OBJECTIVE: We sought to elucidate the relative effects of pattern of ultraviolet radiation exposure, and site and histologic type of the first tumor, on the rate of increase in BCC numbers. METHODS: We used negative binomial regression analysis to study the association of selected variables on the rate of increase in BCC numbers in 266 Caucasian patients who first presented with a tumor on the head/neck or trunk with nodular or superficial histology. RESULTS: Patients with an initial truncal BCC with superficial histology demonstrated significantly faster increases in BCC numbers than did patients with other site and histology combinations. CONCLUSIONS: These data indicate that site and histology define subsets of patients with BCC.
BACKGROUND:Patients with basal cell carcinoma (BCC) frequently develop further tumors during follow-up. OBJECTIVE: We sought to elucidate the relative effects of pattern of ultraviolet radiation exposure, and site and histologic type of the first tumor, on the rate of increase in BCC numbers. METHODS: We used negative binomial regression analysis to study the association of selected variables on the rate of increase in BCC numbers in 266 Caucasian patients who first presented with a tumor on the head/neck or trunk with nodular or superficial histology. RESULTS:Patients with an initial truncal BCC with superficial histology demonstrated significantly faster increases in BCC numbers than did patients with other site and histology combinations. CONCLUSIONS: These data indicate that site and histology define subsets of patients with BCC.
Authors: Lawrence F Kuklinski; Shufeng Li; Margaret R Karagas; Wen-Kai Weng; Bernice Y Kwong Journal: J Am Acad Dermatol Date: 2017-08-02 Impact factor: 11.527
Authors: Andrea Watson; Paul Kent; Murad Alam; Amy S Paller; David M Umbach; Joon Won Yoon; Philip M Iannaccone; David O Walterhouse Journal: Mol Cancer Date: 2009-11-30 Impact factor: 27.401