Literature DB >> 15761256

Adenovirus-based genetic vaccines for biodefense.

Julie L Boyer1, Gary Kobinger, James M Wilson, Ronald G Crystal.   

Abstract

The robust host responses elicited against transgenes encoded by (E1-)(E3-) adenovirus (Ad) gene transfer vectors can be used to develop Ad-based vectors as platform technologies for vaccines against potential bioterror pathogens. This review focuses on pathogens of major concern as bioterror agents and why Ad vectors are ideal as anti-bioterror vaccine platforms, providing examples from our laboratories of using Ad vectors as vaccines against potential bioterror pathogens and how Ad vectors can be developed to enhance vaccine efficacy in the bioterror war.

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Year:  2005        PMID: 15761256     DOI: 10.1089/hum.2005.16.157

Source DB:  PubMed          Journal:  Hum Gene Ther        ISSN: 1043-0342            Impact factor:   5.695


  22 in total

1.  Protective immunity against tularemia provided by an adenovirus-vectored vaccine expressing Tul4 of Francisella tularensis.

Authors:  Ravinder Kaur; Shan Chen; Maria T Arévalo; Qingfu Xu; Yanping Chen; Mingtao Zeng
Journal:  Clin Vaccine Immunol       Date:  2012-01-25

2.  Epitopes expressed in different adenovirus capsid proteins induce different levels of epitope-specific immunity.

Authors:  Anja Krause; Ju H Joh; Neil R Hackett; Peter W Roelvink; Joseph T Bruder; Thomas J Wickham; Imre Kovesdi; Ronald G Crystal; Stefan Worgall
Journal:  J Virol       Date:  2006-06       Impact factor: 5.103

Review 3.  Induction of T cell immunity by cutaneous genetic immunization with recombinant lentivector.

Authors:  Yukai He; Louis D Falo
Journal:  Immunol Res       Date:  2006       Impact factor: 2.829

Review 4.  Genetic medicine strategies to protect against bioterrorism.

Authors:  Julie L Boyer; Ronald G Crystal
Journal:  Trans Am Clin Climatol Assoc       Date:  2006

5.  A new complementing cell line for replication-incompetent E1-deleted adenovirus propagation.

Authors:  Qingfu Xu; Maria T Arevalo; Michael E Pichichero; Mingtao Zeng
Journal:  Cytotechnology       Date:  2006-11-18       Impact factor: 2.058

Review 6.  Developing live vaccines against plague.

Authors:  Wei Sun; Kenneth L Roland; Roy Curtiss
Journal:  J Infect Dev Ctries       Date:  2011-09-14       Impact factor: 0.968

Review 7.  Recent developments for Pseudomonas vaccines.

Authors:  Anurag Sharma; Anja Krause; Stefan Worgall
Journal:  Hum Vaccin       Date:  2011-10-01

Review 8.  Adenovirus: the first effective in vivo gene delivery vector.

Authors:  Ronald G Crystal
Journal:  Hum Gene Ther       Date:  2014-01       Impact factor: 5.695

9.  Nasal inoculation of an adenovirus vector encoding 11 tandem repeats of Abeta1-6 upregulates IL-10 expression and reduces amyloid load in a Mo/Hu APPswe PS1dE9 mouse model of Alzheimer's disease.

Authors:  Hong-Duck Kim; Kazuki Tahara; J Adam Maxwell; Robert Lalonde; Tatsuya Fukuiwa; Kohtaro Fujihashi; Kent R Van Kampen; Fan-Kun Kong; De-chu C Tang; Ken-ichiro Fukuchi
Journal:  J Gene Med       Date:  2007-02       Impact factor: 4.565

10.  Adenovirus F protein as a delivery vehicle for botulinum B.

Authors:  Beata Clapp; Sarah Golden; Massimo Maddaloni; Herman F Staats; David W Pascual
Journal:  BMC Immunol       Date:  2010-07-07       Impact factor: 3.615

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