OBJECTIVE: To report on the identification, recruitment, and enrollment of adolescent survivors of childhood cancer into an ongoing randomized controlled trial (RCT) of health promotion. METHODS: A total of 244 adolescents were contacted by mail and telephone to assess their trial eligibility. Data were collected with respect to each adolescent's demographics and trial recruitment efforts (frequency and intensity of telephone call contact); exclusion and randomization status were tracked throughout. RESULTS:Thirty-one percent of adolescents were ultimately randomized in the trial and 69% were excluded from randomization (13% were ineligible, 33% refused to participate, 22% were unreachable or nonresponsive, that is, did not respond to trial mailings or telephone calls, and less than 1% were withdrawn prior to randomization). Among all eligible adolescents, the trial's consent rate was 49%. Adolescents excluded owing to refusal resided the farthest away from the intervention site and experienced the least amount of telephone call contact time. The primary reasons for trial refusal were lack of interest in health promotion (28%) and lack of time to participate (23%). CONCLUSIONS:Health promotion RCTs among adolescent survivors of childhood cancer may help prevent and control the onset and severity cancer-treatment-related late effects. However, trial success may be contingent upon tracing nonresponsive adolescents and reducing and eliminating barriers to participation.
RCT Entities:
OBJECTIVE: To report on the identification, recruitment, and enrollment of adolescent survivors of childhood cancer into an ongoing randomized controlled trial (RCT) of health promotion. METHODS: A total of 244 adolescents were contacted by mail and telephone to assess their trial eligibility. Data were collected with respect to each adolescent's demographics and trial recruitment efforts (frequency and intensity of telephone call contact); exclusion and randomization status were tracked throughout. RESULTS: Thirty-one percent of adolescents were ultimately randomized in the trial and 69% were excluded from randomization (13% were ineligible, 33% refused to participate, 22% were unreachable or nonresponsive, that is, did not respond to trial mailings or telephone calls, and less than 1% were withdrawn prior to randomization). Among all eligible adolescents, the trial's consent rate was 49%. Adolescents excluded owing to refusal resided the farthest away from the intervention site and experienced the least amount of telephone call contact time. The primary reasons for trial refusal were lack of interest in health promotion (28%) and lack of time to participate (23%). CONCLUSIONS: Health promotion RCTs among adolescent survivors of childhood cancer may help prevent and control the onset and severity cancer-treatment-related late effects. However, trial success may be contingent upon tracing nonresponsive adolescents and reducing and eliminating barriers to participation.
Authors: Jacqueline N Casillas; Lindsay F Schwartz; Catherine M Crespi; Patricia A Ganz; Katherine L Kahn; Margaret L Stuber; Roshan Bastani; Faisal Alquaddomi; Deborah L Estrin Journal: J Cancer Surviv Date: 2019-07-26 Impact factor: 4.442
Authors: Darren Mays; Jessica Donze Black; Revonda B Mosher; Aziza T Shad; Kenneth P Tercyak Journal: J Cancer Surviv Date: 2011-02-27 Impact factor: 4.442
Authors: Megan E Pailler; Lynda K Beaupin; Erin Brewer-Spritzer; Pei C Grant; Rachel M Depner; Kathryn Levy; Kelly E Tenzek Journal: J Adolesc Young Adult Oncol Date: 2020-04-07 Impact factor: 2.223
Authors: Jacqueline Casillas; Karen L Syrjala; Patricia A Ganz; Emy Hammond; Alfred C Marcus; Kerry M Moss; Catherine M Crespi; Peiyun Lu; Mary S McCabe; Jennifer S Ford; Linda A Jacobs; Donna Pucci; Steven C Palmer; Amanda M Termuhlen; Lisa Diller; Marci Campbell; Barbara Jones; Debra L Friedman Journal: J Cancer Surviv Date: 2011-11-02 Impact factor: 4.442