Literature DB >> 15757620

Aspirin resistance and a single gene.

Brian K Jefferson1, Jennifer H Foster, Jeanette J McCarthy, Geoffrey Ginsburg, Alex Parker, Kandice Kottke-Marchant, Eric J Topol.   

Abstract

This study examined the association of single nucleotide polymorphisms in 4 candidate genes in a cohort of subjects with aspirin resistance. Aspirin resistance was significantly associated with genetic variation in the platelet surface adenosine 5-diphosphate receptor gene P2Y1.

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Year:  2005        PMID： 15757620     DOI： 10.1016/j.amjcard.2004.11.045

Source DB:  PubMed          Journal:  Am J Cardiol        ISSN： 0002-9149            Impact factor:   2.778


  23 in total

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Review 4.  The PlA1/A2 polymorphism of glycoprotein IIIa in relation to efficacy of antiplatelet drugs: a systematic review and meta-analysis.

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Review 8.  Antithrombotic properties of aspirin and resistance to aspirin: beyond strictly antiplatelet actions.

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Review 9.  A review of aspirin resistance; definition, possible mechanisms, detection with platelet function tests, and its clinical outcomes.

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Review 10.  Pharmacogenetics of aspirin resistance: a comprehensive systematic review.

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