Literature DB >> 15756330

Lysine-enediyne conjugates as photochemically triggered DNA double-strand cleavage agents.

Serguei V Kovalenko1, Igor V Alabugin.   

Abstract

Statistical analysis of DNA-photocleavage by two types of lysine-enediyne conjugates confirms that more double-strand breaks are produced than can be accounted for by coincident single-strand breaks.

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Year:  2005        PMID： 15756330     DOI： 10.1039/b417012a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  6 in total

1.  DNA damage-site recognition by lysine conjugates.

Authors:  Boris Breiner; Jörg C Schlatterer; Igor V Alabugin; Serguei V Kovalenko; Nancy L Greenbaum
Journal:  Proc Natl Acad Sci U S A       Date:  2007-07-30       Impact factor: 11.205

2.  C-lysine conjugates: pH-controlled light-activated reagents for efficient double-stranded DNA cleavage with implications for cancer therapy.

Authors:  Wang-Yong Yang; Boris Breiner; Serguei V Kovalenko; Chi Ben; Mani Singh; Shauna N LeGrand; Qing-Xiang Amy Sang; Geoffrey F Strouse; John A Copland; Igor V Alabugin
Journal:  J Am Chem Soc       Date:  2009-08-19       Impact factor: 15.419

3.  Intracellular DNA damage by lysine-acetylene conjugates.

Authors:  Wang-Yong Yang; Qiang Cao; Catherine Callahan; Catalina Galvis; Qing-Xiang Sang; Igor V Alabugin
Journal:  J Nucleic Acids       Date:  2010-08-09

4.  Fine-tuning alkyne cycloadditions: Insights into photochemistry responsible for the double-strand DNA cleavage via structural perturbations in diaryl alkyne conjugates.

Authors:  Wang-Yong Yang; Samantha A Marrone; Nalisha Minors; Diego A R Zorio; Igor V Alabugin
Journal:  Beilstein J Org Chem       Date:  2011-06-16       Impact factor: 2.883

5.  Oxime esters of 2,6-diazaanthracene-9,10-dione and 4,5-diazafluoren-9-one as photo-induced DNA-cleaving agents.

Authors:  Shang-Shing P Chou; Jui-Chi Juan; Shwu-Chen Tsay; Kuei Pin Huang; Jih Ru Hwu
Journal:  Molecules       Date:  2012-03-15       Impact factor: 4.411

6.  Synthesis of Ionizable Calix[4]arenes for Chelation of Selected Divalent Cations.

Authors:  Markus Blumberg; Karrar Al-Ameed; Erik Eiselt; Sandra Luber; Constantin Mamat
Journal:  Molecules       Date:  2022-02-22       Impact factor: 4.411
  6 in total

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