Nancy Kassam-Adams1, J Felipe Garcia-España, Joel A Fein, Flaura Koplin Winston. 1. TraumaLink: The Pediatric Interdisciplinary Injury Control Research Center, Center for Pediatric Traumatic Stress, Department of Psychology, Division of Biostatistics, The Children's Hospital of Philadelphia, Pennsylvania, USA.
Abstract
BACKGROUND: Elevated, acute heart rate has been related to later posttraumatic stress disorder (PTSD) development in injured adults, but this has not been examined in children and adolescents. Better understanding of the relationship between acute physiological arousal and later child PTSD could help elucidate the etiology of posttrauma responses in children and might identify useful markers for PTSD risk. OBJECTIVE: To evaluate the relationship between heart rate assessed in the emergency department (ED) during normal clinical care and later PTSD outcome in traumatically injured children. DESIGN: Prospective cohort study assessed heart rate at ED triage and PTSD an average of 6 months' postinjury. SETTING: Large, urban pediatric academic medical center in the northeastern United States. PARTICIPANTS: One hundred ninety children and adolescents (aged 8-17 years) hospitalized for traffic-related injury.Main Outcome Measure Clinician-Administered PTSD Scale for Children and Adolescents. RESULTS: The group of children who developed partial or full PTSD had a higher mean +/- SD heart rate at ED triage than those who did not go on to have PTSD (109.6 +/- 22.3 vs 99.7 +/- 18.0 beats per minute). Children with an elevated heart rate (defined as >/=2 SDs higher than the normal resting heart rate for their age and sex) at ED triage were more likely to meet criteria for partial or full PTSD at follow-up, even after adjusting for age, sex, and injury (adjusted odds ratio, 2.4 [95% confidence interval, 1.1-5.4]). CONCLUSION: These results suggest an association between early physiological arousal and the development or persistence of PTSD symptoms in injured children and point to the importance of better understanding the interplay between physiological and psychological functioning after a traumatic stressor.
BACKGROUND: Elevated, acute heart rate has been related to later posttraumatic stress disorder (PTSD) development in injured adults, but this has not been examined in children and adolescents. Better understanding of the relationship between acute physiological arousal and later childPTSD could help elucidate the etiology of posttrauma responses in children and might identify useful markers for PTSD risk. OBJECTIVE: To evaluate the relationship between heart rate assessed in the emergency department (ED) during normal clinical care and later PTSD outcome in traumatically injured children. DESIGN: Prospective cohort study assessed heart rate at ED triage and PTSD an average of 6 months' postinjury. SETTING: Large, urban pediatric academic medical center in the northeastern United States. PARTICIPANTS: One hundred ninety children and adolescents (aged 8-17 years) hospitalized for traffic-related injury.Main Outcome Measure Clinician-Administered PTSD Scale for Children and Adolescents. RESULTS: The group of children who developed partial or full PTSD had a higher mean +/- SD heart rate at ED triage than those who did not go on to have PTSD (109.6 +/- 22.3 vs 99.7 +/- 18.0 beats per minute). Children with an elevated heart rate (defined as >/=2 SDs higher than the normal resting heart rate for their age and sex) at ED triage were more likely to meet criteria for partial or full PTSD at follow-up, even after adjusting for age, sex, and injury (adjusted odds ratio, 2.4 [95% confidence interval, 1.1-5.4]). CONCLUSION: These results suggest an association between early physiological arousal and the development or persistence of PTSD symptoms in injured children and point to the importance of better understanding the interplay between physiological and psychological functioning after a traumatic stressor.
Authors: Betty Pfefferbaum; Carl F Weems; Brandon G Scott; Pascal Nitiéma; Mary A Noffsinger; Rose L Pfefferbaum; Vandana Varma; Amarsha Chakraburtty Journal: Child Youth Care Forum Date: 2013-08-01
Authors: Ruth C Brown; Nicole R Nugent; Sage E Hawn; Karestan C Koenen; Alisa Miller; Ananda B Amstadter; Glenn Saxe Journal: J Pediatr Health Care Date: 2016-01-14 Impact factor: 1.812