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Literature DB >> 15751560

Low-molecular-weight heparins during pregnancy.

Abstract

QUESTION: A few years ago I suffered from pulmonary emboli. My physician recommended I use dalteparin during this pregnancy although, during my previous pregnancy, I had received subcutaneous heparin injections three times daily. Is dalteparin the same as heparin? ANSWER: : Based on the best available evidence from mostly small prospective case series, retrospective reports, and placental perfusion studies, low-molecular-weight heparins (LMWHs), such as dalteparin, are a safe and convenient alternative to heparin during pregnancy for both mothers and fetuses.

Entities: Chemical Disease

Mesh：

Substances：

Year: 2005 PMID： 15751560 PMCID： PMC1472984

Source DB: PubMed Journal: Can Fam Physician ISSN： 0008-350X Impact factor: 3.275

11 in total

Review 1. Antiplatelet drugs for prevention of pre-eclampsia and its consequences: systematic review.

Authors: L Duley; D Henderson-Smart; M Knight; J King
Journal: BMJ Date: 2001-02-10

2. Absence of transplacental passage of the low molecular weight heparin enoxaparin.

Authors: C Dimitrakakis; P Papageorgiou; I Papageorgiou; A Antzaklis; N Sakarelou; S Michalas
Journal: Haemostasis Date: 2000 Sep-Oct

3. Randomised controlled trial of aspirin and aspirin plus heparin in pregnant women with recurrent miscarriage associated with phospholipid antibodies (or antiphospholipid antibodies)

Authors: R Rai; H Cohen; M Dave; L Regan
Journal: BMJ Date: 1997-01-25

4. Postpartum bone mineral density in women treated for thromboprophylaxis with unfractionated heparin or LMW heparin.

Authors: Ville Pettilä; Pekka Leinonen; Antti Markkola; Vilho Hiilesmaa; Risto Kaaja
Journal: Thromb Haemost Date: 2002-02 Impact factor: 5.249

5. Mutations in coagulation factors in women with unexplained late fetal loss.

Authors: I Martinelli; E Taioli; I Cetin; A Marinoni; S Gerosa; M V Villa; M Bozzo; P M Mannucci
Journal: N Engl J Med Date: 2000-10-05 Impact factor: 91.245

6. Third-trimester unexplained intrauterine fetal death is associated with inherited thrombophilia.

Authors: Ariel Many; Ronit Elad; Yuval Yaron; Amiram Eldor; Joseph B Lessing; Michael J Kupferminc
Journal: Obstet Gynecol Date: 2002-05 Impact factor: 7.661

7. Low-molecular-weight heparin versus low-dose aspirin in women with one fetal loss and a constitutional thrombophilic disorder.

Authors: Jean-Christophe Gris; Eric Mercier; Isabelle Quéré; Géraldine Lavigne-Lissalde; Eva Cochery-Nouvellon; Médéric Hoffet; Sylvie Ripart-Neveu; Marie-Laure Tailland; Michel Dauzat; Pierre Marès
Journal: Blood Date: 2004-01-22 Impact factor: 22.113

8. Increased frequency of genetic thrombophilia in women with complications of pregnancy.

Authors: M J Kupferminc; A Eldor; N Steinman; A Many; A Bar-Am; A Jaffa; G Fait; J B Lessing
Journal: N Engl J Med Date: 1999-01-07 Impact factor: 91.245

9. Prospective observational study of bone mineral density during pregnancy: low molecular weight heparin versus control.

Authors: A J Carlin; R G Farquharson; S M Quenby; J Topping; W D Fraser
Journal: Hum Reprod Date: 2004-04-07 Impact factor: 6.918