Literature DB >> 15750996

A novel mycolactone from a clinical isolate of Mycobacterium ulcerans provides evidence for additional toxin heterogeneity as a result of specific changes in the modular polyketide synthase.

Hui Hong1, Jonathan B Spencer, Jessica L Porter, Peter F Leadlay, Tim Stinear.   

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Year:  2005        PMID： 15750996     DOI： 10.1002/cbic.200400339

Source DB:  PubMed          Journal:  Chembiochem        ISSN： 1439-4227            Impact factor:   3.164


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  25 in total

1.  Mycobacterium ulcerans triggers T-cell immunity followed by local and regional but not systemic immunosuppression.

Authors:  Alexandra G Fraga; Andrea Cruz; Teresa G Martins; Egídio Torrado; Margarida Saraiva; Daniela R Pereira; Wayne M Meyers; Françoise Portaels; Manuel T Silva; António G Castro; Jorge Pedrosa
Journal:  Infect Immun       Date:  2010-10-25       Impact factor: 3.441

2.  Total Synthesis of Mycolactones A and B.

Authors:  Fengbin Song; Steve Fidanze; Andrew B Benowitz; Yoshito Kishi
Journal:  Tetrahedron       Date:  2007-06-25       Impact factor: 2.457

3.  "Mycobacterium ulcerans subsp. shinshuense" isolated from a skin ulcer lesion: identification based on 16S rRNA gene sequencing.

Authors:  Kazue Nakanaga; Norihisa Ishii; Koichi Suzuki; Kazunari Tanigawa; Masamichi Goto; Tsutomu Okabe; Hideaki Imada; Akemi Kodama; Tomotada Iwamoto; Hiroshi Takahashi; Hajime Saito
Journal:  J Clin Microbiol       Date:  2007-09-19       Impact factor: 5.948

4.  Highly stereoselective total synthesis of fully hydroxy-protected mycolactones A and B and their stereoisomerization upon deprotection.

Authors:  Guangwei Wang; Ning Yin; Ei-ichi Negishi
Journal:  Chemistry       Date:  2011-03-15       Impact factor: 5.236

5.  Infection with Mycobacterium ulcerans induces persistent inflammatory responses in mice.

Authors:  Martinha S Oliveira; Alexandra G Fraga; Egídio Torrado; António G Castro; João P Pereira; Adhemar Longatto Filho; Fernanda Milanezi; Fernando C Schmitt; Wayne M Meyers; Françoise Portaels; Manuel T Silva; Jorge Pedrosa
Journal:  Infect Immun       Date:  2005-10       Impact factor: 3.441

6.  Evidence for an intramacrophage growth phase of Mycobacterium ulcerans.

Authors:  Egídio Torrado; Alexandra G Fraga; António G Castro; Pieter Stragier; Wayne M Meyers; Françoise Portaels; Manuel T Silva; Jorge Pedrosa
Journal:  Infect Immun       Date:  2006-12-04       Impact factor: 3.441

7.  Scalable and efficient synthesis of the mycolactone core.

Authors:  Katrina L Jackson; Wenju Li; Chi-Li Chen; Yoshito Kishi
Journal:  Tetrahedron       Date:  2010-03-27       Impact factor: 2.457

Review 8.  Buruli ulcer: reductive evolution enhances pathogenicity of Mycobacterium ulcerans.

Authors:  Caroline Demangel; Timothy P Stinear; Stewart T Cole
Journal:  Nat Rev Microbiol       Date:  2009-01       Impact factor: 60.633

Review 9.  The chemistry and biology of mycolactones.

Authors:  Matthias Gehringer; Karl-Heinz Altmann
Journal:  Beilstein J Org Chem       Date:  2017-08-11       Impact factor: 2.883

10.  Mycolactone gene expression is controlled by strong SigA-like promoters with utility in studies of Mycobacterium ulcerans and buruli ulcer.

Authors:  Nicholas J Tobias; Torsten Seemann; Sacha J Pidot; Jessica L Porter; Laurent Marsollier; Estelle Marion; Franck Letournel; Tasnim Zakir; Joseph Azuolas; John R Wallace; Hui Hong; John K Davies; Benjamin P Howden; Paul D R Johnson; Grant A Jenkin; Timothy P Stinear
Journal:  PLoS Negl Trop Dis       Date:  2009-11-24
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