Leiomyosarcoma of the femoral vein in a marathon runner.

Leiomyosarcoma of the femoral vein is a rare tumor. Physicians involved in the care of athletic patients must not be cavalier in evaluating overuse injuries and should endeavor to make a specific diagnosis. If atypical findings, such as generalized extremity swelling, are present, the physician must consider systemic illness including malignancy in apparently healthy, physically active individuals.