Literature DB >> 15750665

Zinc in health and chronic disease.

R Tudor1, P D Zalewski, R N Ratnaike.   

Abstract

Zinc is a trace element essential for the optimal function of a variety of biochemical and physiological processes. Its role in healthy aging is particularly important as it prevents neo plastic cell growth, is involved in mitotic cell division, DNA and RNA repair. Although zinc is widely available in food, the daily intake in many persons may be suboptimal. Other causes of low zinc concentrations may be due to small bowel conditions that cause mucosal damage and thus decrease absorption. Chronic diseases associated with alterations in zinc status are bronchial asthma, rheumatoid arthritis and Alzheimer disease. At present it is uncertain if therapy with zinc would assist in the management of these chronic diseases. In view of the important cellular functions of zinc in the human body, a diet with an adequate zinc content is beneficial in promoting healthy aging and maintaining good health.

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Year:  2005        PMID: 15750665

Source DB:  PubMed          Journal:  J Nutr Health Aging        ISSN: 1279-7707            Impact factor:   4.075


  22 in total

1.  Zinc mediated hepatic stellate cell collagen synthesis reduction through TGF-β signaling pathway inhibition.

Authors:  Min Kang; Lei Zhao; Meiping Ren; Mingming Deng; Changping Li
Journal:  Int J Clin Exp Med       Date:  2015-11-15

2.  Alcoholism causes alveolar macrophage zinc deficiency and immune dysfunction.

Authors:  Ashish J Mehta; Samantha M Yeligar; Lisa Elon; Lou Ann Brown; David M Guidot
Journal:  Am J Respir Crit Care Med       Date:  2013-09-15       Impact factor: 21.405

3.  Zinc supplementation restores PU.1 and Nrf2 nuclear binding in alveolar macrophages and improves redox balance and bacterial clearance in the lungs of alcohol-fed rats.

Authors:  Ashish J Mehta; Pratibha C Joshi; Xian Fan; Lou Ann S Brown; Jeffrey D Ritzenthaler; Jesse Roman; David M Guidot
Journal:  Alcohol Clin Exp Res       Date:  2011-03-29       Impact factor: 3.455

4.  Aging amplifies multiple phenotypic defects in mice with zinc transporter Zip14 (Slc39a14) deletion.

Authors:  Tolunay Beker Aydemir; Catalina Troche; Jinhee Kim; Min-Hyun Kim; Oriana Y Teran; Christiaan Leeuwenburgh; Robert J Cousins
Journal:  Exp Gerontol       Date:  2016-09-16       Impact factor: 4.032

5.  Low Serum Levels of Selenium, Zinc, Iron, and Zinc/Copper Ratio in an Endemic Region of Cutaneous Leishmaniasis in Southwest Iran.

Authors:  Mehdi Sagha Kahvaz; Shahrzad Soltani; Sheyda Soltani; Manuela Colla Carvalheiro; Masoud Foroutan
Journal:  Biol Trace Elem Res       Date:  2020-07-01       Impact factor: 3.738

6.  Chronic alcohol ingestion in rats decreases Krüppel-like factor 4 expression and intracellular zinc in the lung.

Authors:  Tiana V Curry-McCoy; David M Guidot; Pratibha C Joshi
Journal:  Alcohol Clin Exp Res       Date:  2012-09-26       Impact factor: 3.455

7.  Influence of zinc on the biokinetics of (65)Zn in brain and whole body and its bio-distribution in aluminium-intoxicated rats.

Authors:  Neha Singla; D K Dhawan
Journal:  Cell Mol Neurobiol       Date:  2013-11-28       Impact factor: 5.046

8.  Preparation of Pectin-ZnO Nanocomposite.

Authors:  L Shi; S Gunasekaran
Journal:  Nanoscale Res Lett       Date:  2008-10-21       Impact factor: 4.703

9.  Zinc deficiency mediates alcohol-induced alveolar epithelial and macrophage dysfunction in rats.

Authors:  Pratibha C Joshi; Ashish Mehta; Wissam S Jabber; Xian Fan; David M Guidot
Journal:  Am J Respir Cell Mol Biol       Date:  2008-12-23       Impact factor: 6.914

10.  Zinc enhances the number of regulatory T cells in allergen-stimulated cells from atopic subjects.

Authors:  Eva Rosenkranz; Ralf-Dieter Hilgers; Peter Uciechowski; Arnd Petersen; Birgit Plümäkers; Lothar Rink
Journal:  Eur J Nutr       Date:  2015-11-20       Impact factor: 5.614

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