Literature DB >> 1575043

The influence of calcium on the ototoxicity of aminoglycosides.

S Kaus1.   

Abstract

Aminoglycosides in aquarium water produce a temporary impairment of sensitivity in the lateral line organ of fish. If Ca++ ions are supplied at the same time, the impairment in lateral line sensitivity can be alleviated in a dose-dependent manner. This mechanism appears to be based on competitive antagonism.

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Year:  1992        PMID： 1575043     DOI： 10.3109/00016489209100787

Source DB:  PubMed          Journal:  Acta Otolaryngol        ISSN： 0001-6489            Impact factor:   1.494


  2 in total

1.  Extracellular divalent cations modulate aminoglycoside-induced hair cell death in the zebrafish lateral line.

Authors:  Allison B Coffin; Katherine E Reinhart; Kelly N Owens; David W Raible; Edwin W Rubel
Journal:  Hear Res       Date:  2009-03-12       Impact factor: 3.208

2.  Screen of FDA-approved drug library reveals compounds that protect hair cells from aminoglycosides and cisplatin.

Authors:  Anna L Vlasits; Julian A Simon; David W Raible; Edwin W Rubel; Kelly N Owens
Journal:  Hear Res       Date:  2012-08-31       Impact factor: 3.208
  2 in total

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