Literature DB >> 15749677

Mutation of the prothrombin gene and thrombotic events in patients with polycythemia vera or essential thrombocythemia: a cohort study.

Heinz Gisslinger, Marcus Müllner, Ingrid Pabinger, Navide Heis-Vahidi-Fard, Bettina Gisslinger, Andrea Brichta, Thomas Bachleitner-Hofmann, Christine Mannhalter.   

Abstract

The association between a prothrombin mutation and the risk of thrombosis was analyzed in 214 patients with polycythemia vera or essential thrombocythemia. The rate for venous thrombotic events was 14.7/100 patient-years in patients with the prothrombin mutation compared to 0.8 in patients without the mutation (rate ratio 17.5).

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Year:  2005        PMID： 15749677

Source DB:  PubMed          Journal:  Haematologica        ISSN： 0390-6078            Impact factor:   9.941


  6 in total

Review 1.  Risk Factors for and Management of MPN-Associated Bleeding and Thrombosis.

Authors:  Karlyn Martin
Journal:  Curr Hematol Malig Rep       Date:  2017-10       Impact factor: 3.952

2.  Influence of the JAK2 V617F Mutation and Inherited Thrombophilia on the Thrombotic Risk among Patients with Myeloproliferative Disorders.

Authors:  Mihaela Tevet; Razvan Ionescu; Cornel Dragan; Anca Roxana Lupu
Journal:  Maedica (Buchar)       Date:  2015-03

Review 3.  Are MPNs vascular diseases?

Authors:  Guido Finazzi; Valerio De Stefano; Tiziano Barbui
Journal:  Curr Hematol Malig Rep       Date:  2013-12       Impact factor: 3.952

4.  Influence of the JAK2 V617F mutation and inherited thrombophilia on the thrombotic risk among patients with essential thrombocythemia.

Authors:  Valerio De Stefano; Tommaso Za; Elena Rossi; Alessia Fiorini; Angela Ciminello; Claudia Luzzi; Patrizia Chiusolo; Simona Sica; Giuseppe Leone
Journal:  Haematologica       Date:  2009-03-31       Impact factor: 9.941

5.  Antithrombotic therapy for venous thromboembolism in myeloproliferative neoplasms.

Authors:  Valerio De Stefano; Guido Finazzi; Tiziano Barbui
Journal:  Blood Cancer J       Date:  2018-06-26       Impact factor: 11.037

Review 6.  A guideline for the management of specific situations in polycythaemia vera and secondary erythrocytosis: A British Society for Haematology Guideline.

Authors:  Mary F F McMullin; Adam J Mead; Sahra Ali; Catherine Cargo; Frederick Chen; Joanne Ewing; Mamta Garg; Anna Godfrey; Steven Knapper; Donal P McLornan; Jyoti Nangalia; Mallika Sekhar; Frances Wadelin; Claire N Harrison
Journal:  Br J Haematol       Date:  2018-11-13       Impact factor: 6.998
  6 in total

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