| Literature DB >> 15749199 |
Quintino Parisi, Giuseppe G L Biondi-Zoccai, Antonio Abbate, Daniele Santini, Fortunata Vasaturo, Susanna Scarpa, Rossana Bussani, Antonio Maria Leone, Alessandro Petrolini, Furio Silvestri, Luigi M Biasucci, Alfonso Baldi.
Abstract
We report hypoxia-inducible factor-1 (HIF-1) expression in myocardium of patients with recent acute myocardial infarction (AMI), supporting the hypothesis of HIF-1 as a possible mediator of response to ischemia. A potential diagnostic role of determining tissue expression of HIF-1 as a marker of ischemia, and potential therapeutic implications by trying to modulate HIF-1 activity in order to promote beneficial effects of HIF-1 related genes (e.g. expression of vascular endothelial growth factor (VEGF)) may derive.Entities:
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Year: 2005 PMID： 15749199 DOI： 10.1016/j.ijcard.2003.11.038
Source DB: PubMed Journal: Int J Cardiol ISSN： 0167-5273 Impact factor: 4.164