Literature DB >> 15748837

Homing in on intracellular Abeta?

Todd E Golde1, Christopher Janus.   

Abstract

In this issue of Neuron, a study by Billings et al. points to intracellular Abeta as a possible cause of neuronal dysfunction. In a mouse model of Alzheimer's disease, Billings et al. link appearance of intraneuronal Abeta to cognitive impairments and then show that "clearance" of intraneuronal Abeta by anti-Abeta antibodies restores cognitive deficits.

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Year:  2005        PMID： 15748837     DOI： 10.1016/j.neuron.2005.02.013

Source DB:  PubMed          Journal:  Neuron        ISSN： 0896-6273            Impact factor:   17.173


  12 in total

1.  Intraneuronal APP, not free Aβ peptides in 3xTg-AD mice: implications for tau versus Aβ-mediated Alzheimer neurodegeneration.

Authors:  Matthew J Winton; Edward B Lee; Eveline Sun; Margaret M Wong; Susan Leight; Bin Zhang; John Q Trojanowski; Virginia M-Y Lee
Journal:  J Neurosci       Date:  2011-05-25       Impact factor: 6.167

2.  L-type voltage-gated calcium channel blockade with isradipine as a therapeutic strategy for Alzheimer's disease.

Authors:  Thimmappa S Anekonda; Joseph F Quinn; Christopher Harris; Kate Frahler; Teri L Wadsworth; Randall L Woltjer
Journal:  Neurobiol Dis       Date:  2010-09-09       Impact factor: 5.996

3.  ApoHRP-based assay to measure intracellular regulatory heme.

Authors:  Hani Atamna; Marmik Brahmbhatt; Wafa Atamna; Gregory A Shanower; Joseph M Dhahbi
Journal:  Metallomics       Date:  2015-02       Impact factor: 4.526

Review 4.  Abnormal tau, mitochondrial dysfunction, impaired axonal transport of mitochondria, and synaptic deprivation in Alzheimer's disease.

Authors:  P Hemachandra Reddy
Journal:  Brain Res       Date:  2011-07-31       Impact factor: 3.252

5.  FcγRIIb mediates amyloid-β neurotoxicity and memory impairment in Alzheimer's disease.

Authors:  Tae-In Kam; Sungmin Song; Youngdae Gwon; Hyejin Park; Ji-Jing Yan; Isak Im; Ji-Woo Choi; Tae-Yong Choi; Jeongyeon Kim; Dong-Keun Song; Toshiyuki Takai; Yong-Chul Kim; Key-Sun Kim; Se-Young Choi; Sukwoo Choi; William L Klein; Junying Yuan; Yong-Keun Jung
Journal:  J Clin Invest       Date:  2013-06-10       Impact factor: 14.808

Review 6.  Anti-amyloid Aggregation Activity of Natural Compounds: Implications for Alzheimer's Drug Discovery.

Authors:  Xian-Le Bu; Praveen P N Rao; Yan-Jiang Wang
Journal:  Mol Neurobiol       Date:  2015-06-23       Impact factor: 5.590

Review 7.  Amino acids variations in amyloid-beta peptides, mitochondrial dysfunction, and new therapies for Alzheimer's disease.

Authors:  Hani Atamna
Journal:  J Bioenerg Biomembr       Date:  2009-10       Impact factor: 2.945

Review 8.  Mechanisms of neuronal death in disease: defining the models and the players.

Authors:  Elena M Ribe; Esther Serrano-Saiz; Nsikan Akpan; Carol M Troy
Journal:  Biochem J       Date:  2008-10-15       Impact factor: 3.766

Review 9.  Regulation of caspases in the nervous system implications for functions in health and disease.

Authors:  Carol M Troy; Nsikan Akpan; Ying Y Jean
Journal:  Prog Mol Biol Transl Sci       Date:  2011       Impact factor: 4.025

10.  Therapeutic approaches to delay the onset of Alzheimer's disease.

Authors:  Raj Kumar; Hani Atamna
Journal:  J Aging Res       Date:  2011-03-03
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