Literature DB >> 15746738

Complex aortic valve repair as a durable and effective alternative to valve replacement in children with aortic valve disease.

James S Tweddell1, Andrew N Pelech, Peter C Frommelt, Robert D B Jaquiss, George M Hoffman, Kathleen A Mussatto, S Bert Litwin.   

Abstract

OBJECTIVE: This study was undertaken to determine the utility of aortic valve repair in children.
METHODS: A retrospective analysis was conducted on aortic valve surgery from 1973 to 2004 at Children's Hospital of Wisconsin.
RESULTS: Procedures were classified as simple repairs (blunt valvotomy, commissurotomy with or without thinning, n = 147), repair of aortic insufficiency with ventricular septal defect (n = 22), complex repairs (any combination of additional procedures including suspension of prolapsed leaflets, leaflet extensions, repair of torn or perforated leaflets, annuloplasty, reduction of sinus of Valsalva plasty, and concomitant repair of supravalvular or subvalvular stenosis, n = 57), and replacements (n = 57, 20 mechanical, 2 porcine, and 35 human valves). Freedoms from reintervention for simple repairs and repair of aortic insufficiency with ventricular septal defect at 10 years were 86% +/- 5% and 93.3% +/- 6%, respectively. For complex valve repair, freedoms from reintervention at 1, 5, and 10 years were 94% +/- 3%, 85% +/- 6%, and 44% +/- 15%, versus 96% +/- 3%, 77% +/- 9%, and 77% +/- 9% for valve replacement ( P = .3). At intermediate follow-up, patients with complex valve repair had a residual gradient of 20 +/- 21 mm Hg, and 94% were free of severe aortic insufficiency. Residual aortic stenosis ( P < .05) but not the preoperative diagnosis of combined aortic stenosis and insufficiency predicted the need for reintervention.
CONCLUSION: Freedom from reintervention after complex valve repairs was not different from that after valve replacement, with acceptable residual aortic stenosis and insufficiency. Simple repairs and repair of aortic insufficiency with ventricular septal defect yielded excellent long-term freedom from reintervention.

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Year:  2005        PMID: 15746738     DOI: 10.1016/j.jtcvs.2004.09.033

Source DB:  PubMed          Journal:  J Thorac Cardiovasc Surg        ISSN: 0022-5223            Impact factor:   5.209


  5 in total

1.  The novel two-dimensional strain reflects improvement and remodeling of left-ventricular function better than conventional echocardiographic parameters after aortic valve repair in pediatric patients.

Authors:  Yaping Mi; Tanja Rädle-Hurst; Axel Rentzsch; Diana Aicher; Hans Joachim Schäfers; Hashim Abdul-Khaliq
Journal:  Pediatr Cardiol       Date:  2012-06-02       Impact factor: 1.655

2.  Predicting left ventricular recovery after replacement of a regurgitant aortic valve in pediatric and young adult patients: is it ever too late?

Authors:  Daniel A Cox; Kara Walton; Peter J Bartz; James S Tweddell; Peter C Frommelt; Michael G Earing
Journal:  Pediatr Cardiol       Date:  2012-10-09       Impact factor: 1.655

3.  Intraoperative Echocardiography for Congenital Aortic Valve Repair: Predictors of Early Reoperation.

Authors:  Kenan W D Stern; Matthew T White; George R Verghese; Pedro J Del Nido; Tal Geva
Journal:  Ann Thorac Surg       Date:  2015-06-30       Impact factor: 4.330

4.  Outcomes of the infant Ross procedure for congenital aortic stenosis followed into adolescence.

Authors:  Robert W Elder; Jan M Quaegebeur; Emile A Bacha; Jonathan M Chen; Francois Bourlon; Ismee A Williams
Journal:  J Thorac Cardiovasc Surg       Date:  2012-10-11       Impact factor: 5.209

Review 5.  Syndrome of Ventricular Septal Defect and Aortic Regurgitation - A 22-Year Review of its Management.

Authors:  Sivakumar Krishnasamy; Sivakumar Sivalingam; Jeswant Dillon; Raja Amin Raja Mokhtar; A Yakub; Ramesh Singh
Journal:  Braz J Cardiovasc Surg       Date:  2021-12-03
  5 in total

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