Literature DB >> 15746369

Environmental DNA fragment conferring early and increased sporulation and antibiotic production in Streptomyces species.

Asuncion Martinez1, Steven J Kolvek, Joern Hopke, Choi Lai Tiong Yip, Marcia S Osburne.   

Abstract

Here we describe the rep gene, isolated from an environmental DNA library, which when transformed into Streptomyces species resulted in increased production of secondary metabolites and accelerated sporulation. We show that Streptomyces lividans strains bearing rep are particularly useful as expression hosts for heterologous antibiotic production.

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Year:  2005        PMID: 15746369      PMCID: PMC1065173          DOI: 10.1128/AEM.71.3.1638-1641.2005

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN: 0099-2240            Impact factor:   4.792


  12 in total

1.  Expression and isolation of antimicrobial small molecules from soil DNA libraries.

Authors:  I A MacNeil; C L Tiong; C Minor; P R August; T H Grossman; K A Loiacono; B A Lynch; T Phillips; S Narula; R Sundaramoorthi; A Tyler; T Aldredge; H Long; M Gilman; D Holt; M S Osburne
Journal:  J Mol Microbiol Biotechnol       Date:  2001-04

2.  Cloning the soil metagenome: a strategy for accessing the genetic and functional diversity of uncultured microorganisms.

Authors:  M R Rondon; P R August; A D Bettermann; S F Brady; T H Grossman; M R Liles; K A Loiacono; B A Lynch; I A MacNeil; C Minor; C L Tiong; M Gilman; M S Osburne; J Clardy; J Handelsman; R M Goodman
Journal:  Appl Environ Microbiol       Date:  2000-06       Impact factor: 4.792

3.  Recombinant environmental libraries provide access to microbial diversity for drug discovery from natural products.

Authors:  Sophie Courtois; Carmela M Cappellano; Maria Ball; Francois-Xavier Francou; Philippe Normand; Gérard Helynck; Asuncion Martinez; Steven J Kolvek; Joern Hopke; Marcia S Osburne; Paul R August; Renaud Nalin; Michel Guérineau; Pascale Jeannin; Pascal Simonet; Jean-Luc Pernodet
Journal:  Appl Environ Microbiol       Date:  2003-01       Impact factor: 4.792

4.  Engineering of primary carbon metabolism for improved antibiotic production in Streptomyces lividans.

Authors:  Michael J Butler; Per Bruheim; Srdjan Jovetic; Flavia Marinelli; Pieter W Postma; Mervyn J Bibb
Journal:  Appl Environ Microbiol       Date:  2002-10       Impact factor: 4.792

5.  Modulation of actinorhodin biosynthesis in Streptomyces lividans by glucose repression of afsR2 gene transcription.

Authors:  E S Kim; H J Hong; C Y Choi; S N Cohen
Journal:  J Bacteriol       Date:  2001-04       Impact factor: 3.490

6.  Evolutionary relationships between sugar kinases and transcriptional repressors in bacteria.

Authors:  F Titgemeyer; J Reizer; A Reizer; M H Saier
Journal:  Microbiology (Reading)       Date:  1994-09       Impact factor: 2.777

7.  Regulation of PTS gene expression by the homologous transcriptional regulators, Mlc and NagC, in Escherichia coli (or how two similar repressors can behave differently).

Authors:  J Plumbridge
Journal:  J Mol Microbiol Biotechnol       Date:  2001-07

8.  Alteration of the synthesis of the Clp ATP-dependent protease affects morphological and physiological differentiation in Streptomyces.

Authors:  V de Crécy-Lagard; P Servant-Moisson; J Viala; C Grandvalet; P Mazodier
Journal:  Mol Microbiol       Date:  1999-05       Impact factor: 3.501

9.  The ram-dependence of Streptomyces lividans differentiation is bypassed by copper.

Authors:  B J Keijser; G P van Wezel; G W Canters; T Kieser; E Vijgenboom
Journal:  J Mol Microbiol Biotechnol       Date:  2000-10

10.  Genetically modified bacterial strains and novel bacterial artificial chromosome shuttle vectors for constructing environmental libraries and detecting heterologous natural products in multiple expression hosts.

Authors:  Asuncion Martinez; Steven J Kolvek; Choi Lai Tiong Yip; Joern Hopke; Kara A Brown; Ian A MacNeil; Marcia S Osburne
Journal:  Appl Environ Microbiol       Date:  2004-04       Impact factor: 4.792

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  8 in total

1.  Size Does Matter: Application-driven Approaches for Soil Metagenomics.

Authors:  Kavita S Kakirde; Larissa C Parsley; Mark R Liles
Journal:  Soil Biol Biochem       Date:  2010-11-01       Impact factor: 7.609

Review 2.  Triggers and cues that activate antibiotic production by actinomycetes.

Authors:  Hua Zhu; Stephanie K Sandiford; Gilles P van Wezel
Journal:  J Ind Microbiol Biotechnol       Date:  2013-08-02       Impact factor: 3.346

3.  Repression of antibiotic production and sporulation in Streptomyces coelicolor by overexpression of a TetR family transcriptional regulator.

Authors:  Delin Xu; Nicolas Seghezzi; Catherine Esnault; Marie-Joelle Virolle
Journal:  Appl Environ Microbiol       Date:  2010-10-08       Impact factor: 4.792

4.  Natural Product Discovery through Improved Functional Metagenomics in Streptomyces.

Authors:  Hala A Iqbal; Lila Low-Beinart; Joseph U Obiajulu; Sean F Brady
Journal:  J Am Chem Soc       Date:  2016-07-22       Impact factor: 15.419

5.  Mass spectrometric screening of transcriptional regulators involved in antibiotic biosynthesis in Streptomyces coelicolor A3(2).

Authors:  Sung-Soo Park; Yung-Hun Yang; Eunjung Song; Eun-Jung Kim; Woo Seong Kim; Jae Kyung Sohng; Hei Chan Lee; Kwang Kyoung Liou; Byung-Gee Kim
Journal:  J Ind Microbiol Biotechnol       Date:  2009-05-26       Impact factor: 3.346

6.  The ROK family regulator Rok7B7 pleiotropically affects xylose utilization, carbon catabolite repression, and antibiotic production in streptomyces coelicolor.

Authors:  Magdalena A Świątek; Jacob Gubbens; Giselda Bucca; Eunjung Song; Yung-Hun Yang; Emma Laing; Byung-Gee Kim; Colin P Smith; Gilles P van Wezel
Journal:  J Bacteriol       Date:  2013-01-04       Impact factor: 3.490

Review 7.  Enhancing metagenomics investigations of microbial interactions with biofilm technology.

Authors:  Robert J C McLean; Kavita S Kakirde
Journal:  Int J Mol Sci       Date:  2013-11-11       Impact factor: 5.923

Review 8.  Metabolic profiling as a tool for prioritizing antimicrobial compounds.

Authors:  Changsheng Wu; Young Hae Choi; Gilles P van Wezel
Journal:  J Ind Microbiol Biotechnol       Date:  2015-09-03       Impact factor: 3.346

  8 in total

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