| Literature DB >> 15746369 |
Asuncion Martinez1, Steven J Kolvek, Joern Hopke, Choi Lai Tiong Yip, Marcia S Osburne.
Abstract
Here we describe the rep gene, isolated from an environmental DNA library, which when transformed into Streptomyces species resulted in increased production of secondary metabolites and accelerated sporulation. We show that Streptomyces lividans strains bearing rep are particularly useful as expression hosts for heterologous antibiotic production.Entities:
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Year: 2005 PMID: 15746369 PMCID: PMC1065173 DOI: 10.1128/AEM.71.3.1638-1641.2005
Source DB: PubMed Journal: Appl Environ Microbiol ISSN: 0099-2240 Impact factor: 4.792