Literature DB >> 15745828

From a total synthesis of cepabactin and its 3:1 ferric complex to the isolation of a 1:1:1 mixed complex between iron (III), cepabactin and pyochelin.

Cédric Klumpp1, Alain Burger, Gaëtan L Mislin, Mohamed A Abdallah.   

Abstract

A novel and straightforward total synthesis of cepabactin and its iron (III) complex is described. The latter compound was compared and identified to that obtained from the cultures of Burkholderia cepacia. On treatment of the growth medium of two different strains of B. cepacia with ferric chloride, we have isolated and characterized an unexpected mixed complex of iron (III), cepabactin and pyochelin.

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Year:  2005        PMID: 15745828     DOI: 10.1016/j.bmcl.2005.01.034

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  7 in total

Review 1.  Siderophore-based iron acquisition and pathogen control.

Authors:  Marcus Miethke; Mohamed A Marahiel
Journal:  Microbiol Mol Biol Rev       Date:  2007-09       Impact factor: 11.056

Review 2.  Mammalian siderophores, siderophore-binding lipocalins, and the labile iron pool.

Authors:  Colin Correnti; Roland K Strong
Journal:  J Biol Chem       Date:  2012-03-02       Impact factor: 5.157

3.  Synthesis and iron sequestration equilibria of novel exocyclic 3-hydroxy-2-pyridinone donor group siderophore mimics.

Authors:  James M Harrington; Sumathi Chittamuru; Suraj Dhungana; Hollie K Jacobs; Aravamudan S Gopalan; Alvin L Crumbliss
Journal:  Inorg Chem       Date:  2010-09-20       Impact factor: 5.165

4.  Stereospecificity of the siderophore pyochelin outer membrane transporters in fluorescent pseudomonads.

Authors:  Françoise Hoegy; Xiaoyun Lee; Sabrina Noel; Didier Rognan; Gaëtan L A Mislin; Cornelia Reimmann; Isabelle J Schalk
Journal:  J Biol Chem       Date:  2009-03-17       Impact factor: 5.157

5.  The Pseudomonas aeruginosa pyochelin-iron uptake pathway and its metal specificity.

Authors:  Armelle Braud; Mélissa Hannauer; Gaëtan L A Mislin; Isabelle J Schalk
Journal:  J Bacteriol       Date:  2009-03-27       Impact factor: 3.490

6.  Bacterial siderophores: the solution stoichiometry and coordination of the Fe(III) complexes of pyochelin and related compounds.

Authors:  Chiu-Fou Tseng; Alain Burger; Gaëtan L A Mislin; Isabelle J Schalk; Steve S-F Yu; Sunney I Chan; Mohamed A Abdallah
Journal:  J Biol Inorg Chem       Date:  2006-03-21       Impact factor: 3.358

7.  Burkholderia pseudomallei known siderophores and hemin uptake are dispensable for lethal murine melioidosis.

Authors:  Brian H Kvitko; Andrew Goodyear; Katie L Propst; Steven W Dow; Herbert P Schweizer
Journal:  PLoS Negl Trop Dis       Date:  2012-06-26
  7 in total

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