Literature DB >> 15745827

Novel beta-(imidazol-4-yl)-beta-amino acids: solid-phase synthesis and study of their inhibitory activity against geranylgeranyl protein transferase type I.

Ashis K Saha1, David W End.   

Abstract

Solid-phase synthesis of imidazolyl-beta-amino acid derivatives is described. Several analogs demonstrated moderate inhibition of geranylgeranyl protein transferase type I (GGPT I).

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Year:  2005        PMID： 15745827     DOI： 10.1016/j.bmcl.2005.01.042

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  2 in total

1.  Synthesis, physical properties and cytotoxicity of stilbene-triazine derivatives containing amino acid groups as fluorescent whitening agents.

Authors:  Maosheng Wan; Shaoli Zhou; Peifu Jiao; Chengbo Cao; Jing Guo
Journal:  J Fluoresc       Date:  2013-06-09       Impact factor: 2.217

Review 2.  Conformationally constrained histidines in the design of peptidomimetics: strategies for the χ-space control.

Authors:  Azzurra Stefanucci; Francesco Pinnen; Federica Feliciani; Ivana Cacciatore; Gino Lucente; Adriano Mollica
Journal:  Int J Mol Sci       Date:  2011-05-03       Impact factor: 5.923
  2 in total

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