Literature DB >> 15744082

Araloside A, an antiulcer constituent from the root bark of Aralia elata.

Eun Bang Lee1, Oon Ja Kim, Sam Sik Kang, Choonsik Jeong.   

Abstract

Araloside A, a potent inhibitor of gastric lesion and ulcer formation in rats, was isolated from the root bark of Aralia elata through a bioassay-guided separation procedure. The compound exhibited significant reduction of HCl.ethanol-induced gastric lesions and aspirin-induced gastric ulcers at oral doses of 50 and 100 mg/kg, respectively. These activities are comparable to those of cimetidine.

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Year:  2005        PMID： 15744082     DOI： 10.1248/bpb.28.523

Source DB:  PubMed          Journal:  Biol Pharm Bull        ISSN： 0918-6158            Impact factor:   2.233


  7 in total

1.  Gastroprotective effect of araloside A on ethanol- and aspirin-induced gastric ulcer in mice: involvement of H+/K+-ATPase and mitochondrial-mediated signaling pathway.

Authors:  Haibo He; Xiaomei Li; Haili Yu; Shu Zhu; Yumin He; Katsuko Komatsu; Dongyan Guo; Xiaoqin Li; Junzhi Wang; Huajun Luo; Daoxiang Xu; Kun Zou
Journal:  J Nat Med       Date:  2018-12-06       Impact factor: 2.343

2.  Prophylactic and curative anti-ulcerogenic activity and the possible mechanisms of action of some desert plants.

Authors:  Reham M El-Meligy; Amani S Awaad; Gamal A Soliman; Sanaa A Kenawy; Saleh I Alqasoumi
Journal:  Saudi Pharm J       Date:  2016-10-19       Impact factor: 4.330

Review 3.  Plants against Helicobacter pylori to combat resistance: An ethnopharmacological review.

Authors:  Doha Abou Baker
Journal:  Biotechnol Rep (Amst)       Date:  2020-05-21

4.  Multiomics analysis of soybean meal induced marine fish enteritis in juvenile pearl gentian grouper, Epinephelus fuscoguttatus ♀ × Epinephelus lanceolatus ♂.

Authors:  Wei Zhang; Beiping Tan; Junming Deng; Zhang Haitao
Journal:  Sci Rep       Date:  2021-12-02       Impact factor: 4.379

5.  Oleanane-triterpenoids from Panax stipuleanatus inhibit NF-κB.

Authors:  Chun Liang; Yan Ding; Seok Bean Song; Jeong Ah Kim; Nguyen Manh Cuong; Jin Yeul Ma; Young Ho Kim
Journal:  J Ginseng Res       Date:  2013-03       Impact factor: 6.060

6.  In vitro Cytotoxicity of Methanol Extract from Aerial Parts of Aralia cachemirica and Purified Continentalic Acid.

Authors:  B S Arora; Ekta Sharma; S K Agrawal; Madhunika Agrawal
Journal:  Indian J Pharm Sci       Date:  2015 Nov-Dec       Impact factor: 0.975

7.  Synergistic Antioxidant Effects of Araloside A and L-Ascorbic Acid on H2O2-Induced HEK293 Cells: Regulation of Cellular Antioxidant Status.

Authors:  Yaqin Tian; Xiuling Zhang; Meiling Du; Fengfeng Li; Manyu Xiao; Wentao Zhang
Journal:  Oxid Med Cell Longev       Date:  2021-07-09       Impact factor: 6.543
  7 in total

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