Literature DB >> 15743972

Kinetic characterization of the glycosyltransferase module of Staphylococcus aureus PBP2.

Dianah Barrett1, Catherine Leimkuhler, Lan Chen, Deborah Walker, Daniel Kahne, Suzanne Walker.   

Abstract

We report the heterologous overexpression and purification of Staphylococcus aureus PBP2 and demonstrate efficient glycan polymerization from lipid II in vitro. S. aureus PBP2 is the first purified gram-positive class A penicillin-binding protein to show good transglycosylase activity. This enables further studies on this important class of enzymes.

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Year:  2005        PMID： 15743972      PMCID： PMC1064046          DOI： 10.1128/JB.187.6.2215-2217.2005

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  18 in total

1.  Lipid II is an intrinsic component of the pore induced by nisin in bacterial membranes.

Authors:  Eefjan Breukink; Hester E van Heusden; Pauline J Vollmerhaus; Ewa Swiezewska; Livia Brunner; Suzanne Walker; Albert J R Heck; Ben de Kruijff
Journal:  J Biol Chem       Date:  2003-03-26       Impact factor: 5.157

Review 2.  Antimicrobial resistance: the example of Staphylococcus aureus.

Authors:  Franklin D Lowy
Journal:  J Clin Invest       Date:  2003-05       Impact factor: 14.808

3.  Lipid II: total synthesis of the bacterial cell wall precursor and utilization as a substrate for glycosyltransfer and transpeptidation by penicillin binding protein (PBP) 1b of Escherichia coli.

Authors:  B Schwartz; J A Markwalder; Y Wang
Journal:  J Am Chem Soc       Date:  2001-11-28       Impact factor: 15.419

4.  An acquired and a native penicillin-binding protein cooperate in building the cell wall of drug-resistant staphylococci.

Authors:  M G Pinho; H de Lencastre; A Tomasz
Journal:  Proc Natl Acad Sci U S A       Date:  2001-08-21       Impact factor: 11.205

5.  Vancomycin analogues active against vanA-resistant strains inhibit bacterial transglycosylase without binding substrate.

Authors:  Lan Chen; Deborah Walker; Binyuan Sun; Yanan Hu; Suzanne Walker; Daniel Kahne
Journal:  Proc Natl Acad Sci U S A       Date:  2003-04-24       Impact factor: 11.205

6.  The glycosyltransferase domain of penicillin-binding protein 2a from Streptococcus pneumoniae catalyzes the polymerization of murein glycan chains.

Authors:  Anne Marie Di Guilmi; Andréa Dessen; Otto Dideberg; Thierry Vernet
Journal:  J Bacteriol       Date:  2003-08       Impact factor: 3.490

7.  The direction of glycan synthesis in a bacterial peptidoglycan.

Authors:  J B Ward; H R Perkins
Journal:  Biochem J       Date:  1973-12       Impact factor: 3.857

8.  Expression and characterization of the isolated glycosyltransferase module of Escherichia coli PBP1b.

Authors:  Dianah S Barrett; Lan Chen; Nadia K Litterman; Suzanne Walker
Journal:  Biochemistry       Date:  2004-09-28       Impact factor: 3.162

9.  In vitro assembly of a complete, pentaglycine interpeptide bridge containing cell wall precursor (lipid II-Gly5) of Staphylococcus aureus.

Authors:  Tanja Schneider; Maria Magdalena Senn; Brigitte Berger-Bächi; Alessandro Tossi; Hans-Georg Sahl; Imke Wiedemann
Journal:  Mol Microbiol       Date:  2004-07       Impact factor: 3.501

10.  A kinetic characterization of the glycosyltransferase activity of Eschericia coli PBP1b and development of a continuous fluorescence assay.

Authors:  Benjamin Schwartz; Jay A Markwalder; Steven P Seitz; Yi Wang; Ross L Stein
Journal:  Biochemistry       Date:  2002-10-15       Impact factor: 3.162
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  21 in total

1.  The direction of glycan chain elongation by peptidoglycan glycosyltransferases.

Authors:  Deborah L Perlstein; Yi Zhang; Tsung-Shing Wang; Daniel E Kahne; Suzanne Walker
Journal:  J Am Chem Soc       Date:  2007-10-03       Impact factor: 15.419

2.  Primer preactivation of peptidoglycan polymerases.

Authors:  Tsung-Shing Andrew Wang; Tania J Lupoli; Yuto Sumida; Hirokazu Tsukamoto; Yihui Wu; Yuriy Rebets; Daniel E Kahne; Suzanne Walker
Journal:  J Am Chem Soc       Date:  2011-05-17       Impact factor: 15.419

3.  Degradation and reconstruction of moenomycin A and derivatives: dissecting the function of the isoprenoid chain.

Authors:  Masaatsu Adachi; Yi Zhang; Catherine Leimkuhler; Binyuan Sun; John V LaTour; Daniel E Kahne
Journal:  J Am Chem Soc       Date:  2006-11-01       Impact factor: 15.419

4.  Monofunctional transglycosylases are not essential for Staphylococcus aureus cell wall synthesis.

Authors:  Patricia Reed; Helena Veiga; Ana M Jorge; Mohammed Terrak; Mariana G Pinho
Journal:  J Bacteriol       Date:  2011-03-25       Impact factor: 3.490

5.  Forming cross-linked peptidoglycan from synthetic gram-negative Lipid II.

Authors:  Matthew D Lebar; Tania J Lupoli; Hirokazu Tsukamoto; Janine M May; Suzanne Walker; Daniel Kahne
Journal:  J Am Chem Soc       Date:  2013-03-13       Impact factor: 15.419

6.  Tuning the moenomycin pharmacophore to enable discovery of bacterial cell wall synthesis inhibitors.

Authors:  Christian M Gampe; Hirokazu Tsukamoto; Emma H Doud; Suzanne Walker; Daniel Kahne
Journal:  J Am Chem Soc       Date:  2013-03-04       Impact factor: 15.419

7.  Importance of the conserved residues in the peptidoglycan glycosyltransferase module of the class A penicillin-binding protein 1b of Escherichia coli.

Authors:  Mohammed Terrak; Eric Sauvage; Adeline Derouaux; Dominique Dehareng; Ahmed Bouhss; Eefjan Breukink; Sylvie Jeanjean; Martine Nguyen-Distèche
Journal:  J Biol Chem       Date:  2008-08-13       Impact factor: 5.157

8.  Characterization of the bifunctional glycosyltransferase/acyltransferase penicillin-binding protein 4 of Listeria monocytogenes.

Authors:  Joanna Zawadzka-Skomial; Zdzislaw Markiewicz; Martine Nguyen-Distèche; Bart Devreese; Jean-Marie Frère; Mohammed Terrak
Journal:  J Bacteriol       Date:  2006-03       Impact factor: 3.490

9.  Specific interaction of the unmodified bacteriocin Lactococcin 972 with the cell wall precursor lipid II.

Authors:  Beatriz Martínez; Tim Böttiger; Tanja Schneider; Ana Rodríguez; Hans-Georg Sahl; Imke Wiedemann
Journal:  Appl Environ Microbiol       Date:  2008-06-06       Impact factor: 4.792

10.  Kinetic characterization of the monofunctional glycosyltransferase from Staphylococcus aureus.

Authors:  Mohammed Terrak; Martine Nguyen-Distèche
Journal:  J Bacteriol       Date:  2006-04       Impact factor: 3.490
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