OBJECTIVE: The authors examined the association between volume of the fusiform gyrus, a region involved in face processing, and the personality trait of extraversion in patients with schizophrenia. METHOD: Male patients (N=24) and age-matched male comparison subjects (N=26) completed NEO Five-Factor Inventory personality measures of extraversion and underwent high-spatial-resolution magnetic resonance imaging of anterior and posterior fusiform gyrus gray matter. RESULTS: Low extraversion scores were significantly correlated with gray matter volume reductions in the right posterior fusiform gyrus for patients but not comparison subjects. CONCLUSIONS: Reduced right posterior fusiform gyrus volume may contribute to disease-related social disturbances, characterized by both low extraversion and reduced sensitivity to human faces.
OBJECTIVE: The authors examined the association between volume of the fusiform gyrus, a region involved in face processing, and the personality trait of extraversion in patients with schizophrenia. METHOD: Male patients (N=24) and age-matched male comparison subjects (N=26) completed NEO Five-Factor Inventory personality measures of extraversion and underwent high-spatial-resolution magnetic resonance imaging of anterior and posterior fusiform gyrus gray matter. RESULTS: Low extraversion scores were significantly correlated with gray matter volume reductions in the right posterior fusiform gyrus for patients but not comparison subjects. CONCLUSIONS: Reduced right posterior fusiform gyrus volume may contribute to disease-related social disturbances, characterized by both low extraversion and reduced sensitivity to human faces.
Authors: Heather M Conklin; Monica E Calkins; Charles W Anderson; Thomas J Dinzeo; William G Iacono Journal: Neuropsychologia Date: 2002 Impact factor: 3.139
Authors: Toshiaki Onitsuka; Martha E Shenton; Kiyoto Kasai; Paul G Nestor; Sarah K Toner; Ron Kikinis; Ferenc A Jolesz; Robert W McCarley Journal: Arch Gen Psychiatry Date: 2003-04
Authors: Chang Uk Lee; Martha E Shenton; Dean F Salisbury; Kiyoto Kasai; Toshiaki Onitsuka; Chandlee C Dickey; Deborah Yurgelun-Todd; Ron Kikinis; Ferenc A Jolesz; Robert W McCarley Journal: Arch Gen Psychiatry Date: 2002-09
Authors: Paul G Nestor; Toshiaki Onitsuka; Ronald J Gurrera; Margaret Niznikiewicz; Melissa Frumin; Martha E Shenton; Robert W McCarley Journal: Schizophr Res Date: 2007-01-16 Impact factor: 4.939
Authors: Giuseppe Iaria; Giorgia Committeri; Concetta Pastorelli; Luigi Pizzamiglio; Kate E Watkins; Antonio Carota Journal: Hum Brain Mapp Date: 2008-03 Impact factor: 5.038