| Literature DB >> 15739568 |
Marthew A Koenig1, Romergryko G Geocadin, Piotr Kulesza, Alessandro Olivi, Henry Brem.
Abstract
Rhabdoid meningioma (RM) is a recently described, aggressive variant of meningioma. The authors report a case of RM occurring in the resection cavity of an unrelated neurosurgical procedure, temporal lobectomy for intractable seizures. The patient presented with intractable headache 10 years after the temporal lobectomy. Imaging revealed a dura-based, uniformly enhancing lesion within the resection cavity. She underwent gross-total resection and the findings of the surgical pathological report were consistent with an RM, with a dramatically elevated MIB-1 index of approximately 50%. The patient's clinical course was complicated by severe pain and communicating hydrocephalus secondary to rapid dissemination of malignant cells throughout the CSF pathways. Despite aggressive measures, including tumor resection, ventriculoperitoneal shunt placement, and the initiation of conventional radiation therapy, the ensuing leptomeningeal carcinomatosis proved to be rapidly fatal.Entities:
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Year: 2005 PMID: 15739568 DOI: 10.3171/jns.2005.102.2.0371
Source DB: PubMed Journal: J Neurosurg ISSN: 0022-3085 Impact factor: 5.115