Literature DB >> 15738978

Therapeutic applications of polymeric artificial cells.

Thomas Ming Swi Chang1.   

Abstract

Polymeric artificial cells have the potential to be used for a wide variety of therapeutic applications, such as the encapsulation of transplanted islet cells to treat diabetic patients. Recent advances in biotechnology, molecular biology, nanotechnology and polymer chemistry are now opening up further exciting possibilities in this field. However, it is also recognized that there are several key obstacles to overcome in bringing such approaches into routine clinical use. This review describes the historical development and principles behind polymeric artificial cells, the present state of the art in their therapeutic application, and the promises and challenges for the future.

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Year:  2005        PMID： 15738978     DOI： 10.1038/nrd1659

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN： 1474-1776            Impact factor:   84.694


  68 in total

Review 1.  From artificial red blood cells, oxygen carriers, and oxygen therapeutics to artificial cells, nanomedicine, and beyond.

Authors:  Thomas M S Chang
Journal:  Artif Cells Blood Substit Immobil Biotechnol       Date:  2012-03-13

Review 2.  Artificial cell microencapsulated stem cells in regenerative medicine, tissue engineering and cell therapy.

Authors:  Zun Chang Liu; Thomas Ming Swi Chang
Journal:  Adv Exp Med Biol       Date:  2010       Impact factor: 2.622

3.  Synthesis and characterization of hemoglobin conjugates with antioxidant enzymes via poly(ethylene glycol) cross-linker (Hb-SOD-CAT) for protection from free radical stress.

Authors:  Venkatareddy Nadithe; You Han Bae
Journal:  Int J Biol Macromol       Date:  2010-08-17       Impact factor: 6.953

Review 4.  50th anniversary of artificial cells: their role in biotechnology, nanomedicine, regenerative medicine, blood substitutes, bioencapsulation, cell/stem cell therapy and nanorobotics.

Authors:  Thomas Ming Swi Chang
Journal:  Artif Cells Blood Substit Immobil Biotechnol       Date:  2007

5.  A bloodless revolution. A growing interest in artificial blood substitutes has resulted in new products that could soon improve transfusion medicine.

Authors:  Andrea Rinaldi
Journal:  EMBO Rep       Date:  2005-08       Impact factor: 8.807

Review 6.  Transplantation of xenogeneic islets: are we there yet?

Authors:  Philip J O'Connell; Peter J Cowan; Wayne J Hawthorne; Shounan Yi; Andrew M Lew
Journal:  Curr Diab Rep       Date:  2013-10       Impact factor: 4.810

Review 7.  Controlled delivery systems: from pharmaceuticals to cells and genes.

Authors:  Elizabeth Rosado Balmayor; Helena Sepulveda Azevedo; Rui L Reis
Journal:  Pharm Res       Date:  2011-03-19       Impact factor: 4.200

8.  Cell-enclosing gelatin-based microcapsule production for tissue engineering using a microfluidic flow-focusing system.

Authors:  Shinji Sakai; Sho Ito; Hitomi Inagaki; Keisuke Hirose; Tomohiro Matsuyama; Masahito Taya; Koei Kawakami
Journal:  Biomicrofluidics       Date:  2011-03-30       Impact factor: 2.800

9.  The immunological properties of stroma-free polyhemolysate containing catalase and superoxide dismutase activities prepared by polymerized bovine stroma-free hemolysate.

Authors:  Hongli Zhu; Qianqian Du; Chao Chen; Thomas Ming Swi Chang
Journal:  Artif Cells Blood Substit Immobil Biotechnol       Date:  2010-04

10.  Cell-membrane mechanics: Vesicles in and tubes out.

Authors:  Marileen Dogterom; Gijsje Koenderink
Journal:  Nat Mater       Date:  2011-07-22       Impact factor: 43.841
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