| Literature DB >> 15737913 |
G Magiorkinis1, D Paraskevis, E Magiorkinis, A-M Vandamme, A Hatzakis.
Abstract
One of the main characteristics of the HIV-1 is its extensive genetic heterogeneity. Intersubtype recombination was first described in 1995 and since then a significant proportion of the HIV-1 isolates was found to comprise mosaic sequences. Re-analysis of 34 full-length HIV-1 intersubtype recombinants, including all "pure" HIV-1 subtypes revealed that 19 of the 34 analyzed mosaics consist of a more complex mosaic pattern than initially described. These findings indicate that the complexity of the HIV-1 recombinants is much greater than previously estimated.Entities:
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Year: 2004 PMID： 15737913 DOI： 10.1016/j.meegid.2004.05.010
Source DB: PubMed Journal: Infect Genet Evol ISSN： 1567-1348 Impact factor: 3.342