| Literature DB >> 15737577 |
I-hsin Su1, Alexander Tarakhovsky.
Abstract
Gene expression, differentiation and the specialized function of various cell types are controlled epigenetically by post-translational histone modifications. These modifications establish a "histone code" that is recognized by various regulatory proteins, thereby creating a stable pattern of gene expression. The focus of this review is to discuss how the chromatin modifications regulate immunoglobulin gene rearrangement and B cell differentiation.Mesh:
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Year: 2005 PMID: 15737577 DOI: 10.1016/j.smim.2005.01.007
Source DB: PubMed Journal: Semin Immunol ISSN: 1044-5323 Impact factor: 11.130