| Literature DB >> 15737187 |
Richard L Eckert1, Michael T Sturniolo, Ann-Marie Broome, Monica Ruse, Ellen A Rorke.
Abstract
Surface epithelial cells, such as the epidermal keratinocyte, undergo a process of terminal cell differentiation that results in the construction of a multilayered epithelium. This epithelium functions to protect the organism from the environment. Transglutaminases, enzymes that catalyze the formation of isopeptide protein-protein cross-links, are key enzymes involved in the construction of this structure. This brief review will focus on the role of these enzymes in constructing the epidermal surface.Mesh：
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Year: 2005 PMID： 15737187 DOI： 10.1111/j.0022-202X.2005.23627.x
Source DB: PubMed Journal: J Invest Dermatol ISSN： 0022-202X Impact factor: 8.551